MATN3
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Official Full Name
matrilin 3 -
Overview
This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains two von Willebrand factor A domains; it is present in the cartilage extracellular matrix and has a role in the development and homeostasis of cartilage and bone. Mutations in this gene result in multiple epiphyseal dysplasia. -
Synonyms
MATN3;matrilin 3;matrilin-3;EDM5;HOA;AV009181;DIPOA;MATN3_HUMAN;OADIP;OS2
Recombinant Proteins
- Human
- Chicken
- Mouse
- Mammalian Cells
- E.coli
- HEK293
- His
- His&T7
- DDK&Myc
- His&Myc
- Avi&Fc&His
Involved Pathway
MATN3 involved in several pathways and played different roles in them. We selected most pathways MATN3 participated on our site, such as ECM proteoglycans,Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with MATN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ECM proteoglycans | COL9A1,FMOD,VCANB,ASPN,MATN4,HAPLN1,DAG1,COMP,LRP4,DMP1 |
| Extracellular matrix organization | TLL2,MUSK,ADAMTS18,LEPRE1,FN1B,COL4A3,MATN4,MATN3B,CEACAM8,DDR1 |
Protein Function
MATN3 has several biochemical functions, for example, calcium ion binding,extracellular matrix structural constituent,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MATN3 itself. We selected most functions MATN3 had, and list some proteins which have the same functions with MATN3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SERPINA1A,FOXO4,TRIM40,ZNF559,VRK2,HP1BP3,CRKL,RASSF7,TLX1,CCDC50 |
| extracellular matrix structural constituent | COL1A1B,LAMB1,PRELP,MEPE,FBN2B,TINAGL1,LAMA4,MGP,COL4A1,COL11A1A |
| calcium ion binding | CELSR1,EFHC1,GM5077,NELL2,MYL9,PCDH2G29,ANXA3,SYTL3,MYL5,PCDH2G1 |
Interacting Protein
MATN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MATN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MATN3.
TCF4;KRTAP10-8;NOTCH2NL;intg_a5_b1_human;COMP
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