MATN1
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Official Full Name
matrilin 1, cartilage matrix protein -
Overview
This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. Mutations of this gene have been associated with variety of inherited chondrodysplasias. -
Synonyms
MATN1;matrilin 1, cartilage matrix protein;CMP, CRTM;cartilage matrix protein;CMP;CRTM
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MATN1-2241C | Recombinant Chicken MATN1 | Mammalian Cells | Chicken | His |
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| MATN1-5783Z | Recombinant Zebrafish MATN1 | Mammalian Cells | Zebrafish | His |
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| MATN1-9587M | Recombinant Mouse MATN1 Protein | Mammalian Cells | Mouse | His |
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| MATN1-2694H | Recombinant Human MATN1 protein(231-480 aa), C-His-tagged | E.coli | Human | His | 231-480 aa |
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| MATN1-5387M | Recombinant Mouse MATN1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| MATN1-5387M-B | Recombinant Mouse MATN1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
MATN1 involved in several pathways and played different roles in them. We selected most pathways MATN1 participated on our site, such as ECM proteoglycans,Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with MATN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ECM proteoglycans | LRP4,MATN3B,BGNA,ACAN,MUSK,ASPN,COL9A1,VCANB,DAG1,MATN3 |
| Extracellular matrix organization | COL8A1,ASPN,COL5A2,COL17A1,CTSG,MFAP2,COMP,COL4A4,CTS7,COL5A3B |
Protein Function
MATN1 has several biochemical functions, for example, extracellular matrix structural constituent,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MATN1 itself. We selected most functions MATN1 had, and list some proteins which have the same functions with MATN1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| extracellular matrix structural constituent | COL5A1,COL2A1A,COL1A1A,COL4A5,COL27A1,LAMA4,TINAGL1,CD4,FBN2B,KAL1 |
| protein binding | GIT2,CIZ1,UQCRH,TESC,FDX1L,CYS1,CSRNP2,KRT33B,HELZ,FAM20C |
Interacting Protein
MATN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MATN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MATN1.
cj035_mouse
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References
- Ehlen, HWA; Sengle, G; et al. Proteolytic Processing Causes Extensive Heterogeneity of Tissue Matrilin Forms. JOURNAL OF BIOLOGICAL CHEMISTRY 284:21545-21556(2009).
- Vincourt, JB; Vignaud, JM; et al. Increased expression of matrilin-3 not only in osteoarthritic articular cartilage but also in cartilage-forming tumors, and down-regulation of SOX9 via epidermal growth factor domain 1-dependent signaling. ARTHRITIS AND RHEUMATISM 58:2798-2808(2008).
