MAST2
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Official Full Name
microtubule associated serine/threonine kinase 2 -
Overview
Microtubule-associated serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the MAST2 gene. The protein encoded by this gene controls TRAF6 and NF-kappaB activity. -
Synonyms
MAST2;microtubule associated serine/threonine kinase 2;microtubule-associated serine/threonine-protein kinase 2;KIAA0807;MAST205;EC 2.7.11.1 3;FLJ39200;MAST 2;MAST 205;Microtubule associated testis specific serine/threonine protein kinase;MTSSK;OTTHUMP00000009697 2;OTTHUMP00000046616;RP4 533D7.1;RP4-533D7.1 2;OTTHUMP00000009697;RP4-533D7.1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MAST2-4457HCL | Recombinant Human MAST2 293 Cell Lysate | HEK293 | Human | Non |
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| MAST2-1548H | Recombinant Human MAST2 protein, His & GST-tagged | E.coli | Human | His&GST | Phe512~Phe785 |
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| MAST2-1549H | Recombinant Human MAST2 Protein, GST-tagged | Insect Cells | Human | GST |
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| MAST2-4132H | Recombinant Human MAST2 Protein (Phe512-Phe785), N-GST tagged | E.coli | Human | GST | Phe512-Phe785 |
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Involved Pathway
MAST2 involved in several pathways and played different roles in them. We selected most pathways MAST2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAST2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MAST2 has several biochemical functions, for example, ATP binding,magnesium ion binding,microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAST2 itself. We selected most functions MAST2 had, and list some proteins which have the same functions with MAST2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | FAM176B,CD177,U2AF1,SFRP4,MTMR2,PRPF4,RNF2,CEP350,DNAJA1,ZFAND6 |
| magnesium ion binding | TOP2A,PRPSAP1,STK11,ABL2,PGM2,ITPK1A,ALPI,FARS2,HPGDS,DUT |
| ATP binding | STK35L,CAMK1,Atp8a2,DDX54,DICER1,BLM,ASNS,P2RX3A,PRPS1,RPS6KA6 |
| phosphatase binding | PPP1R37,SH3GL1,CRY1,ELFN2,PPP1R26,DLG1L,SMAD2,DLG1,PPP1R32,CNST |
| protein serine/threonine kinase activity | CDK16,DCLK2,MAPK14,PIK3CA,RPS6KA4,TSSK6,ULK4,NEK1,RIOK2,OXSR1A |
| microtubule binding | TPPP,KIFC2,KIAA1128,KCNH2A,KRIT1,CAMSAP1A,DNM2,RCC2,FES,GABARAPL2 |
Interacting Protein
MAST2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAST2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAST2.
SLC9A3;CDHR2;SLC9A3;HSP90AB1;GCN1L1;TK1;TPM3;TPM2;TPM1;ACTN2;SUMO2;MXRA7;SMN1;ZNF417;TTN
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References
- Janku, F; Garrido-Laguna, I; et al. Novel Therapeutic Targets in Non-small Cell Lung Cancer. JOURNAL OF THORACIC ONCOLOGY 6:1601-1612(2011).
- Wood-Kaczmar, A; Kraus, M; et al. An alternatively spliced form of glycogen synthase kinase-3 beta is targeted to growing neurites and growth cones. MOLECULAR AND CELLULAR NEUROSCIENCE 42:184-194(2009).
