MARS2

  • Official Full Name

    methionine-tRNA synthetase 2 (mitochondrial)
  • Synonyms

    MetRS;C730026E21Rik
Cat.# Product name Source (Host) Species Tag Protein Length Price
MARS2-1061HCL Recombinant Human MARS2 cell lysate Human Non
Mars2-1765M Recombinant Mouse Mars2 Protein, His-tagged E.coli Mouse His Phe363-Thr586
MARS2-1766H Recombinant Human MARS2 Protein, His&GST-tagged E.coli Human His&GST Phe370-Thr593
Mars2-3963M Recombinant Mouse Mars2 Protein, Myc/DDK-tagged HEK293 Mouse Myc&DDK
MARS2-5503H Recombinant Human MARS2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human Myc&DDK

    Involved Pathway

    MARS2 involved in several pathways and played different roles in them. We selected most pathways MARS2 participated on our site, such as Selenocompound metabolism,Aminoacyl-tRNA biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with MARS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Selenocompound metabolism PAPSS1,MTR,PAPSS2A,TXNRD2,CCBL1,INMT,PAPSS2,SCLY,SPS2,TXNRD3
    Aminoacyl-tRNA biosynthesis PSTK,TARS,EPRS,FARSA,PARS2,FARSB,RARS2,VARS,VARS2,WARS

    Protein Function

    MARS2 has several biochemical functions, for example, ATP binding,methionine-tRNA ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MARS2 itself. We selected most functions MARS2 had, and list some proteins which have the same functions with MARS2. You can find most of the proteins on our site.

    Function Related Protein
    methionine-tRNA ligase activity MARS
    ATP binding MAP2K7,ERBB4,UCKL1A,TEC,ADCY6,FYNA,GLYCTK,PDGFRB,ACTC1,ACVRL1

    Interacting Protein

    MARS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MARS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MARS2.

    Resources

    References

    • Lin, SC; Karoly, ED; et al. The human Delta Np53 isoform triggers metabolic and gene expression changes that activate mTOR and alter mitochondrial function. AGING CELL 12:863-872(2013).
    • Bayat, V; Thiffault, I; et al. Mutations in the Mitochondrial Methionyl-tRNA Synthetase Cause a Neurodegenerative Phenotype in Flies and a Recessive Ataxia (ARSAL) in Humans. PLOS BIOLOGY 10:-(2012).

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