MARCH7
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Official Full Name
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase -
Synonyms
MARCH7;membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase;17393;ENSG00000136536;AXO;AXOT;RNF177;MARCH-VII;2q24.2;DKFZp586F1122;E3 ubiquitin-protein ligase MARCH7;E3 ubiquitin-protein ligase MARCH7;axotrophin;RING finger protein 177;membrane-associated RING-CH protein VII;membrane-associated RING finger protein 7;EC 6.3.2.-
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MARCH7-3586R | Recombinant Rat MARCH7 Protein | Mammalian Cells | Rat | His |
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| MARCH7-6448Z | Recombinant Zebrafish MARCH7 | Mammalian Cells | Zebrafish | His |
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| MARCH7-3242R | Recombinant Rat MARCH7 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| MARCH7-3242R-B | Recombinant Rat MARCH7 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
MARCH7 involved in several pathways and played different roles in them. We selected most pathways MARCH7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MARCH7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
MARCH7 has several biochemical functions, for example, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MARCH7 itself. We selected most functions MARCH7 had, and list some proteins which have the same functions with MARCH7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | TRIM11,NEURL3,MMP10,TRIM25,CREBBP,ADAM8,MMP13,MMP16,NR2F1B,PRICKLE1 |
Interacting Protein
MARCH7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MARCH7 here. Most of them are supplied by our site. Hope this information will be useful for your research of MARCH7.
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References
- Yan, YQ; Jiang, W; et al. Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome. CELL 160:62-73(2015).
- Flach, K; Ramminger, E; et al. Axotrophin/MARCH7 acts as an E3 ubiquitin ligase and ubiquitinates tau protein in vitro impairing microtubule binding. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1842:1527-1538(2014).
