MAR-04
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Official Full Name
membrane-associated ring finger (C3HC4) 4 -
Overview
MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment. -
Synonyms
MAR-04;membrane-associated ring finger (C3HC4) 4;E3 ubiquitin-protein ligase MARCH4;E3 ubiquitin protein ligase MARCH4;BC056494;MGC104908;RNF174;KIAA1399;MARCH 4;MARCH IV;Membrane associated RING CH protein IV;Membrane associated ring finger (C3HC4) 4;Membrane associated RING finger protein 4;mKIAA1399;RING finger protein 174;MARCH4;Mar-04
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Involved Pathway
MAR-04 involved in several pathways and played different roles in them. We selected most pathways MAR-04 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAR-04 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
MAR-04 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MAR-04 itself. We selected most functions MAR-04 had, and list some proteins which have the same functions with MAR-04. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
MAR-04 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAR-04 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAR-04.
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