MANBA
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Official Full Name
mannosidase, beta A, lysosomal -
Overview
This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement. -
Synonyms
MANBA;mannosidase, beta A, lysosomal;beta-mannosidase;mannase;mannanase;lysosomal beta A mannosidase;MANB1
Recombinant Proteins
- Zebrafish
- Rat
- Mouse
- Human
- Mammalian Cells
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MANBA-10506Z | Recombinant Zebrafish MANBA | Mammalian Cells | Zebrafish | His |
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| MANBA-3552R | Recombinant Rat MANBA Protein | Mammalian Cells | Rat | His |
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| MANBA-9489M | Recombinant Mouse MANBA Protein | Mammalian Cells | Mouse | His |
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| MANBA-4523HCL | Recombinant Human MANBA 293 Cell Lysate | HEK293 | Human | Non |
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| MANBA-3208R | Recombinant Rat MANBA Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| MANBA-3208R-B | Recombinant Rat MANBA Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| MANBA-5318M | Recombinant Mouse MANBA Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| MANBA-5318M-B | Recombinant Mouse MANBA Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
MANBA involved in several pathways and played different roles in them. We selected most pathways MANBA participated on our site, such as Other glycan degradation,Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MANBA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysosome | ATP6AP1B,GALC,ATP6V0A2B,ENTPD4,HYAL1,AP4M1,ATP6V0A2,ARSG,ASAH1B,NAGA |
| Other glycan degradation | MAN2B2,GLB1,ENG-1,NEU3.2,FUCA2,NEU3.1,NEU3,FUCA1.2,MAN2B1,MAN2C1 |
Protein Function
MANBA has several biochemical functions, for example, beta-mannosidase activity,mannose binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MANBA itself. We selected most functions MANBA had, and list some proteins which have the same functions with MANBA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| mannose binding | MAN2B1,CD209,LMAN2,CD209A,CD209B,COLEC10,M6PR,Acr,LMAN1,CLEC4M |
Interacting Protein
MANBA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MANBA here. Most of them are supplied by our site. Hope this information will be useful for your research of MANBA.
Resources
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References
- Pei, J; Kahl-McDonagh, M; et al. Brucella dissociation is essential for macrophage egress and bacterial dissemination. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY 4:-(2014).
- Turse, JE; Pei, JW; et al. Lipopolysaccharide-deficient Brucella variants arise spontaneously during infection. FRONTIERS IN MICROBIOLOGY 2:-(2011).
