MAN2A1
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Official Full Name
mannosidase, alpha, class 2A, member 1 -
Overview
golgi enzyme involved in asparagine-linked oligosaccharide processing -
Synonyms
MAN2A1;mannosidase, alpha, class 2A, member 1;alpha-mannosidase 2;3-1;6-alpha-mannosidase;Alpha mannosidase 2;alpha Mannosidase II;AMAN II;Golgi alpha mannosidase II;Golgi alpha-mannosidase II;MA2A1_HUMAN;MAN II;MANA 2;MANA2;MANII;Mann II;Mannosidase alpha class 2A member 1;Mannosidase Two;Mannosyl oligosaccharide 13 16 alpha mannosidase;Mannosyl-oligosaccharide 1;mannosidase alpha 2;alpha-mannosidase II;mannosidase 2, alpha 1;mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase;Manno
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- Wheat Germ
- E.Coli/Yeast
- Mammalian Cells
- HEK293
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MAN2A1-1427H | Recombinant Human MAN2A1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| Man2a1-3375R | Recombinant Rat Man2a1, His-tagged | E.Coli/Yeast | Rat | His | 489 |
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| MAN2A1-6093Z | Recombinant Zebrafish MAN2A1 | Mammalian Cells | Zebrafish | His |
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| MAN2A1-9484M | Recombinant Mouse MAN2A1 Protein | Mammalian Cells | Mouse | His |
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| MAN2A1-4525HCL | Recombinant Human MAN2A1 293 Cell Lysate | HEK293 | Human | Non |
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| MAN2A1-5315M | Recombinant Mouse MAN2A1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| MAN2A1-5315M-B | Recombinant Mouse MAN2A1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
MAN2A1 involved in several pathways and played different roles in them. We selected most pathways MAN2A1 participated on our site, such as N-Glycan biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAN2A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| N-Glycan biosynthesis | STT3B,TUSC3,STT3A,MGAT4C,ALG9,DAD1,MGAT4A,MGAT5B,RPN2,B4GALT2 |
| Metabolic pathways | PKMA,PKM2,MTMR4,PTGS2,ATP6V0CB,ATP5IB,CYP3A25,ALG2,TPI1A,PIGK |
Protein Function
MAN2A1 has several biochemical functions, for example, carbohydrate binding,hydrolase activity, hydrolyzing N-glycosyl compounds,mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MAN2A1 itself. We selected most functions MAN2A1 had, and list some proteins which have the same functions with MAN2A1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity | MAN2A2 |
| carbohydrate binding | CHI3L1,ACAN,SELL,GCKR,Fcer2a,CLEC14A,ZP3,FCN3,KLRB1B,CLEC3B |
| hydrolase activity, hydrolyzing N-glycosyl compounds | TDG.1,MAN2A2,NEIL2,UNGA |
| zinc ion binding | FBXO30,TRIM17,GALT,FBXO30B,PIAS1,TRIM22,USP20,S100A5,PAPLNB,YAF2 |
Interacting Protein
MAN2A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAN2A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAN2A1.
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References
- Guo, J; Li, X; et al. Alteration of N-glycans and Expression of Their Related Glycogenes in the Epithelial-Mesenchymal Transition of HCV29 Bladder Epithelial Cells. MOLECULES 19:20073-20090(2014).
- Yu, YP; Ding, Y; et al. Novel Fusion Transcripts Associate with Progressive Prostate Cancer. AMERICAN JOURNAL OF PATHOLOGY 184:2840-2849(2014).
