MAN1A2
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Official Full Name
mannosidase, alpha, class 1A, member 2 -
Overview
Alpha-mannosidases function at different stages of N-glycan maturation in mammalian cells. See MAN2A1 (MIM 154582) for general information. -
Synonyms
MAN1A2;mannosidase, alpha, class 1A, member 2;mannosyl-oligosaccharide 1,2-alpha-mannosidase IB;MAN1B;Alpha 1,2 mannosidase IB;Mannosidase alpha class 1A member 2;Mannosyl oligosaccharide 1,2 alpha mannosidase IB;Processing alpha 1,2 mannosidase IB;alpha1,2-mannosidase;alpha-1,2-mannosidase IB;processing alpha-1,2-mannosidase IB
Recombinant Proteins
- Human
- Rhesus macaque
- Mus musculus
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MAN1A2-720H | Recombinant Human MAN1A2, GST-tagged | E.coli | Human | GST | 292-641aa | |
| MAN1A2-2656R | Recombinant Rhesus monkey MAN1A2 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| MAN1A2-1050HCL | Recombinant Human MAN1A2 cell lysate | Human | Non |
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| MAN1A2-2476R | Recombinant Rhesus Macaque MAN1A2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| MAN1A2-2476R-B | Recombinant Rhesus Macaque MAN1A2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| MAN1A2-477H | Recombinant Human MAN1A2 Protein, His-tagged | HEK293 | Human | His | Pro58-Arg641 |
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| RFL258MF | Recombinant Full Length Mouse Mannosyl-Oligosaccharide 1,2-Alpha-Mannosidase Ib(Man1A2) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length (1-641) |
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| RFL26323HF | Recombinant Full Length Human Mannosyl-Oligosaccharide 1,2-Alpha-Mannosidase Ib(Man1A2) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-641) |
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Involved Pathway
MAN1A2 involved in several pathways and played different roles in them. We selected most pathways MAN1A2 participated on our site, such as Asparagine N-linked glycosylation,Metabolic pathways,Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAN1A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | AOC1,GMDS,HOGA1,PPT1,AMDHD1,ATP6V1C1,NDUFS8,UGT1AB,LDHBB,CKMT1A |
| Metabolism of proteins | DPH1,CCDC59,TRAPPC4,DPP4,UBA2,KLHDC3,INHA,PCSK1,PPP6R1,SEC61B |
| Protein processing in endoplasmic reticulum | MAN1C1,YOD1,HSPA8,UGGT1,BCAP31,ATF4,RNF185,UBE2G1B,SAR1AB,MAPK8B |
| N-Glycan biosynthesis | MGAT3,FUT8A,B4GALT3,MAN1B1,MAN2A1,MGAT4B,ALG9,MGAT5,MGAT1,MGAT3A |
| Post-translational protein modification | STT3A,GALNTL5,MUC13,SENP5,CBX8,ADAMTSL5,SPON1A,KCNA6,PPP6R1,RNF2 |
| Asparagine N-linked glycosylation | LMAN2,DERL2,CNIH2,ALG10B,TRAPPC9,BET1,NEU4,NANP,MPDU1,CTAGE5 |
Protein Function
MAN1A2 has several biochemical functions, for example, calcium ion binding,mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MAN1A2 itself. We selected most functions MAN1A2 had, and list some proteins which have the same functions with MAN1A2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | MAN1A,MAN1B1,MAN1C1,EDEM2,EDEM1,MAN1A1 |
| calcium ion binding | CDH15,THBS4A,SYT5,NCL,ARSA,CALB2B,PLA2G5,MMP10,VLDLR,OCM2 |
Interacting Protein
MAN1A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAN1A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAN1A2.
FOS;SP1;GTF2F2;SMAD9
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