MAGI1
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Official Full Name
membrane associated guanylate kinase, WW and PDZ domain containing 1 -
Overview
The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
MAGI1;membrane associated guanylate kinase, WW and PDZ domain containing 1;BAI1 associated protein 1 , BAIAP1;membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1;AIP3;BAP1;MAGI 1;TNRC19;WWP3;BAI1-associated protein 1;WW
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MAGI1-3541R | Recombinant Rat MAGI1 Protein | Mammalian Cells | Rat | His |
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| MAGI1-9461M | Recombinant Mouse MAGI1 Protein | Mammalian Cells | Mouse | His |
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| MAGI1-3197R | Recombinant Rat MAGI1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| MAGI1-3197R-B | Recombinant Rat MAGI1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| MAGI1-5301M | Recombinant Mouse MAGI1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| MAGI1-5301M-B | Recombinant Mouse MAGI1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
MAGI1 involved in several pathways and played different roles in them. We selected most pathways MAGI1 participated on our site, such as Rap signaling pathway,Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Rap signaling pathway | VASP,FLT1,PFN1,PIK3CA,NGFR,GNAI1,RALB,GRIN2A,ACTG1,RAP1GAP |
| Tight junction | VMHC,PRKCZ,CDC42L,YBX3,CLDN8,MYH10,MPP5,CTTN,CLDN17,PTENB |
Protein Function
MAGI1 has several biochemical functions, for example, ATP binding,alpha-actinin binding,nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGI1 itself. We selected most functions MAGI1 had, and list some proteins which have the same functions with MAGI1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | XRCC6,PAPSS2A,EPHB3,HIPK3B,PET112L,PSMC1A,LIMK1A,WARS,SMC3,TK1 |
| alpha-actinin binding | ADORA2A,MYOT,KCNN2,XIRP2,PPARG,RARA,ALMS1,PKD2L1,DAG1,KCNA5 |
| protein complex scaffold | SLC9A3R1,CAV1,SEPT2,CAV3,ISCU,DLG1,MAGI3,MPP7,PKP2,GNB2L1 |
| protein binding | TAF9,VPREB1,PSMD5,KANSL2,BRCA2,RNPS1,GPX7,RIPPLY3,CCDC94,RFC5 |
| nucleotide binding | GC3,ATP2B2,ATP1A1A.5,HNRNPH1L,SPATA5,HNRNPA0L,CDC42L2,TRA2A,ABCB3L1,SRSF6B |
Interacting Protein
MAGI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGI1.
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