MAGEC2
-
Official Full Name
melanoma antigen family C, 2 -
Overview
This gene is a member of the MAGEC gene family. It is not expressed in normal tissues, except for testis, and is expressed in tumors of various histological types. This gene and the other MAGEC genes are clustered on chromosome Xq26-q27. -
Synonyms
MAGEC2;melanoma antigen family C, 2;MAGEE1, melanoma antigen, family E, 1, cancer/testis specific;melanoma-associated antigen C2;cancer/testis antigen 10;CT10;MAGE C2;Cancer testis antigen 10;HCA587;Hepatocellular carcinoma associated antigen 587;Hepatocellular carcinoma-associated antigen 587;MAGC2_HUMAN;MAGE C2 antigen;MAGE E1 antigen;MAGE-C2 antigen;MAGE-E1 antigen;Melanoma associated antigen C2;MGC13377;hepatocellular cancer antigen 587;melanoma antigen, family E, 1, cancer/testis specific;MAGEE1
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- Mammalian Cells
- HEK293
- Insect Cells
- His
- Non
- Flag
- His&Fc&Avi
- N-His&C-Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MAGEC2-152H | Recombinant Human MAGEC2 protein, His-tagged | E.coli | Human | His |
|
|
| MAGEC2-191H | Recombinant Human MAGEC2 protein, His-tagged | E.coli | Human | His |
|
|
| MAGEC2-2628R | Recombinant Rhesus monkey MAGEC2 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
|
|
| MAGEC2-4541HCL | Recombinant Human MAGEC2 293 Cell Lysate | HEK293 | Human | Non |
|
|
| MAGEC2-111H | Recombinant Human MAGEC2 protein, His-tagged | E.coli | Human | His | 111-367 aa |
|
| MAGEC2-174H | Recombinant Human MAGEC2 Protein, DDK-tagged | Insect Cells | Human | Flag |
|
|
| MAGEC2-2448R | Recombinant Rhesus Macaque MAGEC2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
|
|
| MAGEC2-2448R-B | Recombinant Rhesus Macaque MAGEC2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
|
||
| MAGEC2-4532H | Recombinant Human MAGEC2 protein, His&Myc-tagged | E.coli | Human | N-His&C-Myc | 1-373aa |
|
| MAGEC2-749HFL | Recombinant Full Length Human MAGEC2 Protein, N-His-tagged | E.coli | Human | His | Full L. |
|
Involved Pathway
MAGEC2 involved in several pathways and played different roles in them. We selected most pathways MAGEC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MAGEC2 has several biochemical functions, for example, protein binding,ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEC2 itself. We selected most functions MAGEC2 had, and list some proteins which have the same functions with MAGEC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PPP3CA,DLG4,Itga10&Itgb1,RNH1,FLCN,SMUG1,MS4A1,CENPH,PDCD5,KCNG3 |
| ubiquitin protein ligase binding | USP2,BAG5,PER1,UBE2J1,MAP1LC3C,ATXN3,CUL3B,UBE2Z,MDM2,RNF40 |
Interacting Protein
MAGEC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEC2.
TRIM28;TP53;UBE2H
Resources
Related Services
Related Products
References
- Chen, YT; Panarelli, NC; et al. Cancer-Testis Antigen Expression in Digestive Tract Carcinomas: Frequent Expression in Esophageal Squamous Cell Carcinoma and Its Precursor Lesions. CANCER IMMUNOLOGY RESEARCH 2:480-486(2014).
- Beard, RE; Abate-Daga, D; et al. Gene Expression Profiling using Nanostring Digital RNA Counting to Identify Potential Target Antigens for Melanoma Immunotherapy. CLINICAL CANCER RESEARCH 19:4941-4950(2013).
