MAGEB6
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Official Full Name
melanoma antigen family B, 6 -
Overview
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is expressed in testis, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. -
Synonyms
MAGEB6;melanoma antigen family B, 6;melanoma-associated antigen B6;cancer/testis antigen family 3;member 4;CT3.4;FLJ40242;MAGE B6;MAGEB6A;Cancer/testis antigen 3.4;MAGEB6 antigen;Melanoma associated antigen B6;MAGE-B6 antigen;cancer/testis antigen family 3, member 4;MAGE-B6
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MAGEB6-698H | Recombinant Human MAGEB6, GST-tagged | E.coli | Human | GST | 1-407aa | |
| MAGEB6-4542HCL | Recombinant Human MAGEB6 293 Cell Lysate | HEK293 | Human | Non |
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| MAGEB6-1053H | Recombinant Human MAGEB6 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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Involved Pathway
MAGEB6 involved in several pathways and played different roles in them. We selected most pathways MAGEB6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEB6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
MAGEB6 has several biochemical functions, for example, molecular_function,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEB6 itself. We selected most functions MAGEB6 had, and list some proteins which have the same functions with MAGEB6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | STT3A,GATC,ARL6IP4,NRSN1,C22orf23,PDS5B,HIST1H4E,COA5,SWSAP1,ACTN2 |
| molecular_function | CLMN,PSTPIP1B,WDR53,CAGE1,SAGB,CARTPT,TMEM107,DDX26B,PTMAA,GM13305 |
Interacting Protein
MAGEB6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEB6 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEB6.
PHC2;HACL1;HTT;ATXN1
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References
- Tjiu, JW; Lin, PJ; et al. SLURP1 mutation-impaired T-cell activation in a family with mal de Meleda. BRITISH JOURNAL OF DERMATOLOGY 164:47-53(2011).
- Suzuki, S; Sasajima, K; et al. MAGE-A protein and MAGE-A10 gene expressions in liver metastasis in patients with stomach cancer. BRITISH JOURNAL OF CANCER 99:350-356(2008).
