MAGEB4
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Official Full Name
melanoma antigen family B, 4 -
Overview
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEB genes are clustered on chromosome Xp22-p21. This gene sequence ends in the first intron of MAGEB1, another family member. This gene is expressed in testis. -
Synonyms
MAGEB4;melanoma antigen family B, 4;melanoma-associated antigen B4;cancer/testis antigen family 3;member 6;CT3.6;melanoma associated antigen B4;MGC33144;MAGE-B4 antigen;cancer/testis antigen family 3, member 6
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MAGEB4-697H | Recombinant Human MAGEB4, GST-tagged | E.coli | Human | GST | 1-346aa | |
| MAGEB4-4543HCL | Recombinant Human MAGEB4 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
MAGEB4 involved in several pathways and played different roles in them. We selected most pathways MAGEB4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEB4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MAGEB4 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEB4 itself. We selected most functions MAGEB4 had, and list some proteins which have the same functions with MAGEB4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SERPINB1A,SSB,MAPKAPK5,RPS6KA2,LARP4,MIF,ZFYVE1,PELO,ZNF227,BFAR |
Interacting Protein
MAGEB4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEB4 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEB4.
TNR;HGS;WDR62;KRT38;MAGEA8;ROCK1;MED21
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References
- Melero, I; Hirschhorn-Cymerman, D; et al. Agonist Antibodies to TNFR Molecules That Costimulate T and NK Cells. CLINICAL CANCER RESEARCH 19:1044-1053(2013).
- Mitsui, J; Nishikawa, H; et al. Two Distinct Mechanisms of Augmented Antitumor Activity by Modulation of Immunostimulatory/Inhibitory Signals. CLINICAL CANCER RESEARCH 16:2781-2791(2010).
