MAGEB3
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Official Full Name
melanoma antigen family B, 3 -
Overview
This gene is a MAGE-B subfamily member of the MAGE gene family. MAGE family member proteins direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. There are two known clusters of MAGE genes on chromosome X. The members of the MAGE-A subfamily are located in the Xq28 region, while the members of the MAGE-B subfamily are clustered in the Xp21 region. -
Synonyms
MAGEB3;melanoma antigen family B, 3;melanoma-associated antigen B3;cancer/testis antigen family 3;member 5;CT3.5;Cancer/testis antigen family 3 member 5;MAGB3_HUMAN;MAGE B3 antigen;MAGE-B3 antigen;Melanoma associated antigen B3;cancer/testis antigen family 3, member 5
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| MAGEB3-696H | Recombinant Human MAGEB3, His-tagged | E.coli | Human | His | 1-346aa | |
| MAGEB3-401H | Recombinant Human MAGEB3 | Mammalian Cells | Human | His |
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| MAGEB3-4544HCL | Recombinant Human MAGEB3 293 Cell Lysate | HEK293 | Human | Non |
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| MAGEB3-3421H | Recombinant Human MAGEB3 Protein, His (Fc)-Avi-tagged | HEK293 | Human | Avi&Fc&His |
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| MAGEB3-3421H-B | Recombinant Human MAGEB3 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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Involved Pathway
MAGEB3 involved in several pathways and played different roles in them. We selected most pathways MAGEB3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
MAGEB3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEB3 itself. We selected most functions MAGEB3 had, and list some proteins which have the same functions with MAGEB3. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
MAGEB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEB3.
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References
- Chen, YC; Hsu, WL; et al. Expression of MAGE-A restricted to testis and ovary or to various cancers in dogs. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 153:26-34(2013).
- Maarof, G; Bouchet-Delbos, L; et al. Interleukin-24 inhibits the plasma cell differentiation program in human germinal center B cells. BLOOD 115:1718-1726(2010).
