MAGEB2
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Official Full Name
melanoma antigen family B, 2 -
Overview
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. -
Synonyms
MAGEB2;melanoma antigen family B, 2;melanoma-associated antigen B2;cancer/testis antigen family 3;member 2;CT3.2;DAM6;DSS/AHC critical interval MAGE superfamily 6;MAGE XP 2;melanoma associated antigen B2;MGC26438;MAGE-B2 antigen;MAGE XP-2 anti
Recombinant Proteins
- Human
- E.coli
- HEK293
- Insect Cells
- Mammalian Cells
- GST
- Non
- His
- Myc
- Avi
- Fc
- Flag
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MAGEB2-695H | Recombinant Human MAGEB2, GST-tagged | E.coli | Human | GST | 1-319aa | |
| MAGEB2-4545HCL | Recombinant Human MAGEB2 293 Cell Lysate | HEK293 | Human | Non |
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| MAGEB2-1264H | Recombinant Human MAGEB2 protein, His&Myc-tagged | Insect Cells | Human | His&Myc | 1-319aa |
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| MAGEB2-1305H | Recombinant Human MAGEB2 protein, His&Myc-tagged | HEK293 | Human | His&Myc | 1-319aa |
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| MAGEB2-1345H | Recombinant Human MAGEB2 Protein, His (Fc)-Avi-tagged | HEK293 | Human | Avi&Fc&His |
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| MAGEB2-1345H-B | Recombinant Human MAGEB2 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| MAGEB2-1723HFL | Recombinant Full Length Human MAGEB2 Protein, C-Flag-tagged | Mammalian Cells | Human | Flag | Full L. |
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Involved Pathway
MAGEB2 involved in several pathways and played different roles in them. We selected most pathways MAGEB2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MAGEB2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEB2 itself. We selected most functions MAGEB2 had, and list some proteins which have the same functions with MAGEB2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PTTG1IP,UBE2O,C11orf46,FLI1,CKMT1,ZFYVE19,PDHB,KCNE4,TCTN2,GRAMD3 |
Interacting Protein
MAGEB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEB2.
RPGRIP1;20475405;RARA;RPL22;FUS;SRP14;RPS19;RPL3;RPL35;RPL28;RPS9;RPL29;RPL34
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References
- Kimkong, I; Avihingsanon, Y; et al. Expression profile of HIN200 in leukocytes and renal biopsy of SLE patients by real-time RT-PCR. LUPUS 18:1066-1072(2009).
- Yagihashi, A; Ohmura, T; et al. Detection of autoantibodies to survivin and livin in sera from patients with breast cancer. CLINICA CHIMICA ACTA 362:125-130(2005).
