MAGEA12
-
Official Full Name
melanoma antigen family A, 12 -
Overview
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified. -
Synonyms
MAGEA12;melanoma antigen family A, 12;MAGE12;melanoma-associated antigen 12;cancer/testis antigen family 1;member 12;CT1.12;MAGE-12 antigen;MAGE12F antigen;cancer/testis antigen 1.12;cancer/testis antigen family 1, member 12
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MAGEA12-28504TH | Recombinant Human MAGEA12 | Wheat Germ | Human | Non | 314 amino acids |
|
| MAGEA12-4556HCL | Recombinant Human MAGEA12 293 Cell Lysate | HEK293 | Human | Non |
|
|
| MAGEA12-2410H | Recombinant Human MAGEA12 Protein, His-tagged | E.coli | Human | His |
|
|
| MAGEA12-294HF | Recombinant Full Length Human MAGEA12 Protein | In Vitro Cell Free System | Human | Full L. 314 amino acids |
|
Involved Pathway
MAGEA12 involved in several pathways and played different roles in them. We selected most pathways MAGEA12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEA12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MAGEA12 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEA12 itself. We selected most functions MAGEA12 had, and list some proteins which have the same functions with MAGEA12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | CAR6,ESPNL,NLRP9C,DSCR4,C8orf42,RPL37,MFHAS1,FSD1L,CCDC18,GM239 |
Interacting Protein
MAGEA12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEA12 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEA12.
NS;STAT5A
Resources
Related Services
Related Products
References
- Nerreter, T; Kochel, C; et al. Dasatinib enhances migration of monocyte-derived dendritic cells by reducing phosphorylation of inhibitory immune receptors Siglec-9 and Siglec-3. EXPERIMENTAL HEMATOLOGY 42:773-782(2014).
- Zhang, QM; He, SJ; et al. Overexpression of MAGE-D4 in colorectal cancer is a potentially prognostic biomarker and immunotherapy target. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 7:3918-3927(2014).
