MAGEA11
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Official Full Name
melanoma antigen family A, 11 -
Overview
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
MAGEA11;melanoma antigen family A, 11;MAGE11;melanoma-associated antigen 11;cancer/testis antigen family 1;member 11;CT1.11;MAGE 11;MAGE 11 antigen;MAGEA 11;melanoma associated antigen 11;MGC10511;MAGE-11 antigen;cancer/testis antigen 1.11;c
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MAGEA11-690H | Recombinant Human MAGEA11, GST-tagged | E.coli | Human | GST | 79-429aa | |
| MAGEA11-4557HCL | Recombinant Human MAGEA11 293 Cell Lysate | HEK293 | Human | Non |
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| MAGEA11-4491H | Recombinant Human MAGEA11 Protein (Met111-Val429), N-His tagged | E.coli | Human | His | Met111-Val429 |
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Involved Pathway
MAGEA11 involved in several pathways and played different roles in them. We selected most pathways MAGEA11 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEA11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
MAGEA11 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEA11 itself. We selected most functions MAGEA11 had, and list some proteins which have the same functions with MAGEA11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PARP1,PEX11B,MARVELD2,SETD8,KIRREL3,LINGO1B,TRAK1,CEP70,STAT2,ZFAND6 |
Interacting Protein
MAGEA11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEA11 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEA11.
TRMT1;TCEA2;CLUAP1;SH2D4A;COX7A2L;PHYH;NOL4;PB2;PB1;NP;ACTN1;TRIM27;IL11;PRDX3;AKR1C3;CDKN2B
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References
- Lee, OJ; Son, SM; et al. CEACAM6 as detected by the AP11 antibody is a marker notable for mucin-producing adenocarcinomas. VIRCHOWS ARCHIV 466:151-159(2015).
- Uzdensky, A; Demyanenko, S; et al. Expression of proteins involved in epigenetic regulation in human cutaneous melanoma and peritumoral skin. TUMOR BIOLOGY 35:8225-8233(2014).
