MAEA
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Official Full Name
macrophage erythroblast attacher -
Overview
This gene product mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. This protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Two immunologically related isoforms of erythroblast macrophage protein with apparent molecular weights of 33 kD and 36 kD were detected in macrophage membranes; this gene encodes the larger isoform. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. -
Synonyms
MAEA;macrophage erythroblast attacher;EMP;1110030D19Rik;Cell proliferation inducing gene 5 protein;Cell proliferation-inducing gene 5 protein;Erythroblast macrophage protein;HLC 10;HLC-10;HLC10;Human lung cancer oncogene 10 protein;Lung cancer related protein 10;MAEA_HUMAN;MGC93683;PIG5;OTTHUMP00000217706;OTTHUMP00000217707;OTTHUMP00000217708;OTTHUMP00000217709;OTTHUMP00000217710;OTTHUMP00000217711;OTTHUMP00000217716;OTTHUMP00000217718;proliferation-inducing gene 5;lung cancer-related protein 10;erythrobl;EMLP
Recombinant Proteins
- Human
- Chicken
- Rhesus macaque
- Rat
- Mouse
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
MAEA involved in several pathways and played different roles in them. We selected most pathways MAEA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAEA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MAEA has several biochemical functions, for example, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAEA itself. We selected most functions MAEA had, and list some proteins which have the same functions with MAEA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | CAP2,STK38L,FRG1,NEXN,INO80,GSN,GSNB,PLS3,ACE,FBXO25 |
Interacting Protein
MAEA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAEA here. Most of them are supplied by our site. Hope this information will be useful for your research of MAEA.
Ypel5
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References
- Weiner, M; Trondle, J; et al. Improvement of constraint-based flux estimation during L-phenylalanine production with Escherichia coli using targeted knock-out mutants. BIOTECHNOLOGY AND BIOENGINEERING 111:1406-1416(2014).
- Kyriacou, S; Kontoleontos, E; et al. Evolutionary algorithm based optimization of hydraulic machines utilizing a state-of-the-art block coupled CFD solver and parametric geometry and mesh generation tools. 27TH IAHR SYMPOSIUM ON HYDRAULIC MACHINERY AND SYSTEMS (IAHR 2014), PTS 1-7 22:-(2014).
