MAD2L1BP
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Official Full Name
MAD2L1 binding protein -
Overview
The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. -
Synonyms
MAD2L1BP;MAD2L1 binding protein;MAD2L1-binding protein;CMT2;dJ261G23.1;KIAA0110;Caught by MAD2 protein;MAD2L1 binding protein isoform 2;MGC11282;OTTHUMP00000016496;RP1 261G23.6;OTTHUMP00000221652;RP1-261G23.6
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- T7
- His
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
MAD2L1BP involved in several pathways and played different roles in them. We selected most pathways MAD2L1BP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAD2L1BP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MAD2L1BP has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAD2L1BP itself. We selected most functions MAD2L1BP had, and list some proteins which have the same functions with MAD2L1BP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | KTN1,SCRN2,GAB3,FGFR2,USP10,PPP2R5D,HNRNPAB,ZNF649,ARHGEF15,RPH3AL |
Interacting Protein
MAD2L1BP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAD2L1BP here. Most of them are supplied by our site. Hope this information will be useful for your research of MAD2L1BP.
MAD2L1;MAD1L1;PPIA;Trip13;ARHGAP32;MAD1L1;h0y2u5_human;FRYL;ITGA2;YWHAQ;GGCX;PLXNA3;AFF1;TTC3;PLAUR;MST1R;CRYZ;CAMK1
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References
- Chao, WCH; Kulkarni, K; et al. Structure of the mitotic checkpoint complex. NATURE 484:208-U89(2012).
- Guo, YL; Zhang, XM; et al. Functional evaluation of missense variations in the human MAD1L1 and MAD2L1 genes and their impact on susceptibility to lung cancer. JOURNAL OF MEDICAL GENETICS 47:616-622(2010).
