MAD1
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Official Full Name
Mad1p -
Synonyms
MAD1;Mad1p;hMAD1;HsMAD1;MAD1L1;Mitotic arrest deficient 1;Mitotic checkpoint MAD1 protein homolog;Mitotic spindle assembly checkpoint protein MAD1;PIG9;Tax binding protein 181;TP53I9;Tumor protein p53 inducible protein 9;TXBP181;Coiled-coil protein involved in the spindle-assembly checkpoint;phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex;forms a complex with Mad2p
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Involved Pathway
MAD1 involved in several pathways and played different roles in them. We selected most pathways MAD1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
MAD1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MAD1 itself. We selected most functions MAD1 had, and list some proteins which have the same functions with MAD1. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
MAD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAD1.
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References
- Fava, LL; Kaulich, M; et al. Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint. EMBO JOURNAL 30:3322-3336(2011).
- Nakaya, T; Kuwahara, K; et al. Critical Role of Pcid2 in B Cell Survival through the Regulation of MAD2 Expression. JOURNAL OF IMMUNOLOGY 185:5180-5187(2010).
