LSM7
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Official Full Name
LSM7 homolog, U6 small nuclear RNA associated -
Overview
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. -
Synonyms
LSM7;LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae);U6 snRNA-associated Sm-like protein LSm7;YNL147W
Recombinant Proteins
- Chicken
- Zebrafish
- Mouse
- Human
- Mammalian Cells
- HEK293
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LSM7-1481C | Recombinant Chicken LSM7 | Mammalian Cells | Chicken | His |
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| LSM7-4443Z | Recombinant Zebrafish LSM7 | Mammalian Cells | Zebrafish | His |
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| LSM7-9336M | Recombinant Mouse LSM7 Protein | Mammalian Cells | Mouse | His |
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| LSM7-9170HCL | Recombinant Human LSM7 293 Cell Lysate | HEK293 | Human | Non |
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| Lsm7-3859M | Recombinant Mouse Lsm7 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| LSM7-5023H | Recombinant Human LSM7 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| LSM7-5229M | Recombinant Mouse LSM7 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| LSM7-5229M-B | Recombinant Mouse LSM7 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
LSM7 involved in several pathways and played different roles in them. We selected most pathways LSM7 participated on our site, such as RNA degradation,Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with LSM7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Spliceosome | CHERP,RBM25,DHX15,SNRPB2,SRSF5,PRPF31,SRSF7B,TTC6,DDX23,SNRPF |
| RNA degradation | PARN,LSM4,DIS3,PNPT1,LSM5,BTG2,CNOT8,DCP1B,EXOSC2,SKIV2L2 |
Protein Function
LSM7 has several biochemical functions, for example, contributes_to RNA binding,U6 snRNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LSM7 itself. We selected most functions LSM7 had, and list some proteins which have the same functions with LSM7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to RNA binding | SMX5,NUDT21,CPSF6 |
| U6 snRNA binding | LSM4,DDX39B,LSM2,PRPF8,RBM22,LSM8,EIF5A,SART3,PRPF4 |
| protein binding | FKBP6,FBXL5,EIF5A,APOO,CUTC,ZNF625,SLC11A2,RASSF2,SELP,RND1 |
Interacting Protein
LSM7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LSM7 here. Most of them are supplied by our site. Hope this information will be useful for your research of LSM7.
LSM5;SNRPD3;LSM2;LSM4
Resources
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References
- Chowdhury, A; Kalurupalle, S; et al. Pat1 contributes to the RNA binding activity of the Lsm1-7-Pat1 complex. RNA-A PUBLICATION OF THE RNA SOCIETY 20:1465-1475(2014).
- Perez-Santangelo, S; Mancini, E; et al. Role for LSM genes in the regulation of circadian rhythms. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:15166-15171(2014).
