LSM14A
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Official Full Name
LSM14A, SCD6 homolog A (S. cerevisiae) -
Overview
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. -
Synonyms
LSM14A;LSM14A, SCD6 homolog A (S. cerevisiae);C19orf13, chromosome 19 open reading frame 13 , FAM61A, family with sequence similarity 61, member A , LSM14 homolog A (SCD6, S. cerevisiae);protein LSM14 homolog A;DKFZP434D1335;RAP55;RAP55A;AlphaSNBP;C19orf13;Chromosome 19 open reading frame 13;FAM61A;Family with sequence similarity 61 member A;LSM14 homolog A (SCD6 S cerevisiae);LSM14 homolog A;Protein FAM61A;Protein SCD6 homolog;Putative alpha synuclein binding protein;RNA associated protein 55;SCD6 homolog A (S cerevisiae);hRAP55;hRAP55A;RNA-associated protein 55;RNA-associated protein 55A;putative alpha-synuclein-binding protein;family with sequence similarity 61, member A
Recombinant Proteins
- Chicken
- Rhesus macaque
- Human
- Mouse
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Myc&DDK
- GST
Involved Pathway
LSM14A involved in several pathways and played different roles in them. We selected most pathways LSM14A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LSM14A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
LSM14A has several biochemical functions, for example, double-stranded DNA binding,double-stranded RNA binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LSM14A itself. We selected most functions LSM14A had, and list some proteins which have the same functions with LSM14A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| single-stranded RNA binding | POLR2GL,CBX4,IFIT5,CBX6,AGO2,HMGB1,ANXA1,HNRNPA1,CNBP,CBX8 |
| double-stranded DNA binding | AKAP8,TDG,TRP53,SP8B,GTF2H4,PYDC3,ZNF638,XRCC5,EGFR,CRY1 |
| poly(A) RNA binding | METTL16,HIST1H4H,FBL,SFPQ,CSRP1,SRP14,XRN1,WDR46,C4BPA,SART3 |
| double-stranded RNA binding | LRRFIP1,SUPV3L1,AGO3,AGO2,PRKRIP1,MSN,APTX,OAS1A,IFIH1,DDX58 |
Interacting Protein
LSM14A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LSM14A here. Most of them are supplied by our site. Hope this information will be useful for your research of LSM14A.
Lsm14a;deoB;q81yc1_bacan;bosutinib;imatinib;ssrna_ug
Resources
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References
- Li, ZH; Chen, R; et al. LSM14A inhibits porcine reproductive and respiratory syndrome virus (PRRSV) replication by activating IFN-beta signaling pathway in Marc-145. MOLECULAR AND CELLULAR BIOCHEMISTRY 399:247-256(2015).
- Chan, JK; Kiet, TK; et al. MiR-378 as a biomarker for response to anti-angiogenic treatment in ovarian cancer. GYNECOLOGIC ONCOLOGY 133:568-574(2014).
