LNX1
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Official Full Name
ligand of numb-protein X 1, E3 ubiquitin protein ligase -
Overview
This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containin -
Synonyms
LNX1;ligand of numb-protein X 1, E3 ubiquitin protein ligase;ligand of numb protein X , ligand of numb protein X 1 , LNX;E3 ubiquitin-protein ligase LNX;MPDZ;PDZRN2;numb-binding protein 1;PDZ domain-containing ring finger protein 2;multi-PDZ-doma
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LNX1-4460Z | Recombinant Zebrafish LNX1 | Mammalian Cells | Zebrafish | His |
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| LNX1-9168M | Recombinant Mouse LNX1 Protein | Mammalian Cells | Mouse | His |
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| LNX1-4704HCL | Recombinant Human LNX1 293 Cell Lysate | HEK293 | Human | Non |
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| LNX1-5124M | Recombinant Mouse LNX1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| LNX1-5124M-B | Recombinant Mouse LNX1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
LNX1 involved in several pathways and played different roles in them. We selected most pathways LNX1 participated on our site, such as Notch signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with LNX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Notch signaling pathway | JAG1A,KAT2A,ADAM17,NOTCH4,APH1C,JAG2B,NOTCH1B,NOTCH2,MFAP2,DTX1 |
Protein Function
LNX1 has several biochemical functions, for example, PDZ domain binding,ligase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LNX1 itself. We selected most functions LNX1 had, and list some proteins which have the same functions with LNX1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| PDZ domain binding | PLEKHA1,TBC1D10A,GRIK2,SNTA1,ATP2B1B,SLC26A6,LIN7B,FZD8,PLEKHA2,GNG12 |
| ubiquitin-protein transferase activity | TRIM23,UBR3,MUL1,TRAF4B,RC3H2,RNF144AB,TRAF4A,AMFR,UBE2G1,SIAH1A |
| protein binding | OPRK1,DTNB,C1orf65,CCL11,APOBEC2B,CIB3,DCAF11,PPAP2B,WIPF1,TRAF2 |
| ligase activity | TMEM129,TRIM71,NAPRT1,RNF138,UBE3A,UBE2G1B,UBE2F,HERC4,RNF146,PPIL2 |
| zinc ion binding | TRIM17,RAG1,RNF19B,NR4A2A,ZCCHC4,PRKCBB,ADH5,RNF17,BTY,ITGB1BP2 |
Interacting Protein
LNX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LNX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LNX1.
MAGEB18;PCBD1;AIMP2;TRIP13
Resources
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References
- Wolting, CD; Griffiths, EK; et al. Biochemical and Computational Analysis Of LNX1 Interacting Proteins. PLOS ONE 6:-(2011).
- Flynn, M; Saha, O; et al. Molecular evolution of the LNX gene family. BMC EVOLUTIONARY BIOLOGY 11:-(2011).
