LMOD1
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Official Full Name
leiomodin 1 (smooth muscle) -
Overview
The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks.The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves disease and thyroid-associated ophthalmopathy. -
Synonyms
LMOD1;leiomodin 1 (smooth muscle);leiomodin-1;1D;64kD;D1;64 kDa autoantigen 1D3;SM LMOD;SMLMOD;Smooth muscle leiomodin;Thyroid associated ophthalmopathy autoantigen;64 kDa autoantigen 1D;64 kDa autoantigen D1;leiomodin, muscle form;leimodin 1 (smooth muscle);thyroid and eye muscle autoantigen D1 (64kD);thyroid-associated ophthalmopathy autoantigen;SM-LMOD
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LMOD1-4706HCL | Recombinant Human LMOD1 293 Cell Lysate | HEK293 | Human | Non |
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| LMOD1-1308H | Recombinant Human LMOD1 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| LMOD1-1308H-B | Recombinant Human LMOD1 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| LMOD1-2841H | Recombinant Human LMOD1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| Lmod1-3802M | Recombinant Mouse Lmod1 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| LMOD1-496HFL | Active Recombinant Full Length Human LMOD1 Protein, C-Flag-tagged | Mammalian Cells | Human | Flag | Full L. |
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Involved Pathway
LMOD1 involved in several pathways and played different roles in them. We selected most pathways LMOD1 participated on our site, such as Muscle contraction,Smooth Muscle Contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with LMOD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Muscle contraction | ANXA6,VIML,TNNI2A.1,MYBPC2,DES,DMD,MYL9,TNNI2B.1,TNNT3A,DESMB |
| Smooth Muscle Contraction | MYL6B,SORBS3 |
Protein Function
LMOD1 has several biochemical functions, for example, actin binding,tropomyosin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LMOD1 itself. We selected most functions LMOD1 had, and list some proteins which have the same functions with LMOD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | ADD3,MYH7,SPTB,CAP2,PLS3,POF1B,GSN,MACF1,GCET2,FBXO25 |
| tropomyosin binding | TNNT2A,PYCARD,LMOD2A,NEBL,TMOD1,LMOD3,TNNT1,TMOD2,TMOD3,S100A6 |
Interacting Protein
LMOD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LMOD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LMOD1.
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References
- Boczkowska, M; Rebowski, G; et al. Actin Filament Nucleation by Smooth Muscle Leiomodin-1. BIOPHYSICAL JOURNAL 104:645A-645A(2013).
- Nanda, V; Miano, JM; et al. Leiomodin 1, a New Serum Response Factor-dependent Target Gene Expressed Preferentially in Differentiated Smooth Muscle Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 287:2459-2467(2012).
