LIN52
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Official Full Name
lin-52 homolog -
Synonyms
LIN52;lin-52 homolog (C. elegans);C14orf46, chromosome 14 open reading frame 46;protein lin-52 homolog;C14orf46;c14_5549
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- Mouse
- Mammalian Cells
- HEK293
- His
- Non
- Avi
- Fc
- DDK
- Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LIN52-1607H | Recombinant Human LIN52 | Mammalian Cells | Human | His |
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| LIN52-1802C | Recombinant Chicken LIN52 | Mammalian Cells | Chicken | His |
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| LIN52-4868Z | Recombinant Zebrafish LIN52 | Mammalian Cells | Zebrafish | His |
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| LIN52-4731HCL | Recombinant Human LIN52 293 Cell Lysate | HEK293 | Human | Non |
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| LIN52-3367H | Recombinant Human LIN52 Protein, His (Fc)-Avi-tagged | HEK293 | Human | Avi&Fc&His |
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| LIN52-3367H-B | Recombinant Human LIN52 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| Lin52-3786M | Recombinant Mouse Lin52 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| LIN52-4252H | Recombinant Human LIN52 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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Involved Pathway
LIN52 involved in several pathways and played different roles in them. We selected most pathways LIN52 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,G0 and Early G1, which may be useful for your reference. Also, other proteins which involved in the same pathway with LIN52 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| G0 and Early G1 | E2F4,DYRK1A,MYBL2,PIANP,LIN37,LIN9,TOP2A,LIN54 |
| Cell cycle | TCTN2,SPDL1,SMAD3A,CCND1,CDC14AB,MCM2,ANAPC1,SMAD3B,SFN,TUBGCP5 |
| Polo-like kinase mediated events | FOXM1,LIN37,LIN9 |
| G2/M Transition | CLASP1A,TSGA14,BORA,CENPJ,PLK4,CDK11B,TCTN2,CEP70,CEP76,CLASP1 |
| Mitotic G2-G2/M phases | CDK11A,NUMA1,TUBGCP4,FOXM1,TUBGCP5,LIN9,TUBGCP2,TCTN2,CDK11B,TUBGCP3 |
| Cell Cycle, Mitotic | CKS1B,RANGAP1B,SGOL2,CETN2,CCDC99,TUBGCP5,CKAP5,TSGA14,GINS3,ENSAB |
| Mitotic G1-G1/S phases | LIN9,DYRK1A,LIN37,LIN54,MYBL2,TOP2A,MYCA |
Protein Function
LIN52 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by LIN52 itself. We selected most functions LIN52 had, and list some proteins which have the same functions with LIN52. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
LIN52 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LIN52 here. Most of them are supplied by our site. Hope this information will be useful for your research of LIN52.
RBL2;Lin54;MYBL2;LIN9;LIN54;LIN37
Resources
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References
- Doggett, K; Jiang, JQ; et al. Wake-up-call, a lin-52 paralogue, and Always early, a lin-9 homologue physically interact, but have opposing functions in regulating testis-specific gene expression. DEVELOPMENTAL BIOLOGY 355:381-393(2011).
- Sandoval, R; Pilkinton, M; et al. Deletion of the p107/p130-binding domain of Mip130/LIN-9 bypasses the requirement for CDK4 activity for the dissociation of Mip130/LIN-9 from p107/p130-E2F4 complex. EXPERIMENTAL CELL RESEARCH 315:2914-2920(2009).
