LETMD1
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Official Full Name
LETM1 domain containing 1 -
Overview
This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. -
Synonyms
LETMD1;LETM1 domain containing 1;LETM1 domain-containing protein 1;cervical cancer 1 protooncogene;HCCR1;1110019O13Rik;Cervical cancer 1 proto oncogene protein;Cervical cancer proto oncogene 2 protein;DKFZp586A011;HCCR 2;HCCR2;HCRR 2;HCRR2;Regulator of TP53;cervical cancer proto-oncogene 2 protein;cervical cancer 1 proto-oncogene protein p40;HCCR-1;HCCR-2;HCRR-2
Recombinant Proteins
- Human
- Mouse
- Bovine
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LETMD1-29425TH | Recombinant Human LETMD1, His-tagged | E.coli | Human | His | 183-330 a.a. |
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| LETMD1-9058M | Recombinant Mouse LETMD1 Protein | Mammalian Cell | Mouse | His |
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| LETMD1-4771HCL | Recombinant Human LETMD1 293 Cell Lysate | HEK293 | Human | Non |
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| LETMD1-4175H | Recombinant Human LETMD1 Protein (Pro162-Asn347), N-His tagged | E.coli | Human | His | Pro162-Asn347 |
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| LETMD1-5051M | Recombinant Mouse LETMD1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| LETMD1-5051M-B | Recombinant Mouse LETMD1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| RFL15547BF | Recombinant Full Length Bovine Letm1 Domain-Containing Protein 1(Letmd1) Protein, His-Tagged | E.coli expression system | Bovine | His | Full L. Full Length (1-360) |
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Involved Pathway
LETMD1 involved in several pathways and played different roles in them. We selected most pathways LETMD1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LETMD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
LETMD1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LETMD1 itself. We selected most functions LETMD1 had, and list some proteins which have the same functions with LETMD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | REST,HSPBP1,SH2D1B,TBX5,CBL,TCEB3,TDRD9,BST2,SNX12,GMCL1P1 |
Interacting Protein
LETMD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LETMD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LETMD1.
REEP5;SH2D1A;HCK;RAB5C;Rab5b;Ypel5;NCBP1;Cdc37;Gpsm1;Anapc2;Cenpq;Ormdl2;Cxxc1;Tsc1;JRKL
Resources
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References
- Schlickum, S; Moghekar, A; et al. LETM1, a gene deleted in Wolf-Hirschhorn syndrome, encodes an evolutionarily conserved mitochondrial protein. GENOMICS 83:254-261(2004).
