LCLAT1

  • Official Full Name

    lysocardiolipin acyltransferase 1
  • Synonyms

    LCLAT1;lysocardiolipin acyltransferase 1;26756;ENSG00000172954;LYCAT;AGPAT8;ALCAT1;1AGPAT8;UNQ1849;HSRG1849;2p23.1;FLJ37965;lysocardiolipin acyltransferase 1;lysocardiolipin acyltransferase 1;1-AGPAT 8;1-AGP acyltransferase 8;acyl-CoA:lysocardiolipin acyltransferase 1;1-acylglycerol-3-phosphate O-acyltransferase 8;EC 2.3.1.51
Cat.# Product name Source (Host) Species Tag Protein Length Price
LCLAT1-2719C Recombinant Chicken LCLAT1 Mammalian Cells Chicken His
LCLAT1-2954H Recombinant Human LCLAT1 Full Length Transmembrane protein, His-tagged E.coli Human His Full L. 1-414aa
RFL21888MF Recombinant Full Length Mouse Lysocardiolipin Acyltransferase 1(Lclat1) Protein, His-Tagged E.coli Mus musculus His Full L. Full Length (1-376)
RFL29890HF Recombinant Full Length Human Lysocardiolipin Acyltransferase 1(Lclat1) Protein, His-Tagged E.coli Human His Full L. Full Length (1-414)
RFL35335GF Recombinant Full Length Chicken Lysocardiolipin Acyltransferase 1(Lclat1) Protein, His-Tagged E.coli Chicken His Full L. Full Length (1-378)
RFL8378DF Recombinant Full Length Danio Rerio Lysocardiolipin Acyltransferase 1(Lclat1) Protein, His-Tagged E.coli zebrafish His Full L. Full Length (1-388)

    Involved Pathway

    LCLAT1 involved in several pathways and played different roles in them. We selected most pathways LCLAT1 participated on our site, such as Glycerolipid metabolism,Glycerophospholipid metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with LCLAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways BCO1L,COX7B2,GNE,INPP5A,MAT2B,POLR2EB,PLA2G2D,SDSL,POLR2J2,PYGMA
    Glycerolipid metabolism PPAP2C,LYCAT,MBOAT1,DAK,AGPAT3,PPAP2CB,PPAP2B,MBOAT2,AGPAT1,DGKG
    Glycerophospholipid metabolism PNPLA6,AGPAT3,PLA2G15,MBOAT2B,CDS1,DGKQ,PLA2G4F,PNPLA7,PLA2G2F,LPCAT3

    Protein Function

    LCLAT1 has several biochemical functions, for example, 1-acylglycerol-3-phosphate O-acyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LCLAT1 itself. We selected most functions LCLAT1 had, and list some proteins which have the same functions with LCLAT1. You can find most of the proteins on our site.

    Function Related Protein
    1-acylglycerol-3-phosphate O-acyltransferase activity AGPAT4,AGPAT1,AGPAT2,AGPAT3,LPCAT2,LYCAT,AGPAT5,ABHD5,AGPAT9L,AGPAT9

    Interacting Protein

    LCLAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LCLAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LCLAT1.

    Resources

    References

    • Xia, Y; Hong, HF; et al. Label-free quantitative proteomic analysis of right ventricular remodeling in infant Tetralogy of Fallot patients. JOURNAL OF PROTEOMICS 84:78-91(2013).
    • Li, J; Liu, XL; et al. Lysocardiolipin acyltransferase 1 (ALCAT1) controls mitochondrial DNA fidelity and biogenesis through modulation of MFN2 expression. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:6975-6980(2012).

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