LAMC1
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Official Full Name
Laminin Subunit Gamma-1 -
Overview
Laminins are major proteins in the basal lamina (one of the layers of the basement membrane), a protein network foundation for most cells and organs. The laminins are an important and biologically active part of the basal lamina, influencing cell differen -
Synonyms
LAMA 1;LAMA;LAMA1;LAMB1;Lamc3;LAMC3_HUMAN;Laminin A chain;Laminin alpha 1;Laminin alpha 1 chain;Laminin B1 chain;Laminin subunit beta 1;Laminin subunit gamma-3;Laminin-12 subunit gamma;Laminin-14 subunit gamma;Laminin-15 subunit gamma;Laminin, gamma 1;laminin
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rat
- E.coli
- HEK293
- Wheat Germ
- Mammalian Cell
- In Vitro Cell Free System
- HEK293T
- Mamanlian cells
- His
- Myc&DDK
- Non
- Flag
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LAMC1-19H | Recombinant Human LAMC1 protein, His-tagged | E.coli | Human | His | Ile521~Pro772 | |
| LAMC1-12H | Recombinant Human LAMC1 protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| LAMC1-27945TH | Recombinant Human LAMC1 | Wheat Germ | Human | Non | 39 amino acids |
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| LAMC1-9548Z | Recombinant Zebrafish LAMC1 | Mammalian Cell | Zebrafish | His |
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| LAMC1-4827HCL | Recombinant Human LAMC1 293 Cell Lysate | HEK293 | Human | Non |
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| Lamc1-232M | Recombinant Mouse Lamc1 Protein, His-tagged | E.coli | Mouse | His | Glu1228~Arg1404 |
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| Lamc1-233R | Recombinant Rat Lamc1 Protein, His-tagged | E.coli | Rat | His | Glu1283~Asp1551 |
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| LAMC1-2632H | Recombinant Human LAMC1 protein(1071-1400 aa), C-His-tagged | E.coli | Human | His | 1071-1400 aa |
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| LAMC1-275HF | Recombinant Full Length Human LAMC1 Protein | In Vitro Cell Free System | Human | Full L. 39 amino acids |
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| Lamc1-3748M | Recombinant Mouse Lamc1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| LAMC1-3869H | Recombinant Human LAMC1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| LAMC1-9215HFL | Recombinant Full Length Human LAMC1 protein, Flag-tagged | Mamanlian cells | Human | Flag | Full L. |
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Involved Pathway
LAMC1 involved in several pathways and played different roles in them. We selected most pathways LAMC1 participated on our site, such as PIK-Akt signaling pathway,Focal adhesion,ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with LAMC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Focal adhesion | MYL2,MYL9B,PAK6,GRB2B,ACTB2,SHC2,MLCK2,LAMB2,SHC3,COL6A2 |
| Toxoplasmosis | LAMB1,LAMB4,TAB2,HSPA1A,HSPA8,LAMA1,MAP3K7,PIK3CD,MAPK13,LAMA5 |
| PIK-Akt signaling pathway | PIK3CD,MTOR,IL2RA,COL6A5,GNG8,ANGPT2,GNGT1,GRB2,YWHAH,FGFR3 |
| Amoebiasis | PLCB2,ITGB2L,RAB5C,COL4A3,CTSG,SERPINB10,COL4A1,C9,COL5A2,IL-8 |
| Prion diseases | IL1B,Hc,C8G,MAP2K1,PRKACB,IL6,C1QB,C7,C1QC,IL1A |
| ECM-receptor interaction | CHAD,FN1A,SV2B,THBS3A,THBS4A,LAMA1,ITGAV,GP9,COL1A1,ITGB5 |
| Pathways in cancer | PIAS2,LAMA4,WNT6,WNT7A,CASP8,CXCR4,RALB,GNG5,Ar,PRKACG |
| Small cell lung cancer | TRP53,TRAF3,CCNE2,APAF1,TRAF5,BCL2L1,ITGAV,XIAP,FHIT,LAMA5 |
Protein Function
LAMC1 has several biochemical functions, for example, extracellular matrix structural constituent,glycosphingolipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LAMC1 itself. We selected most functions LAMC1 had, and list some proteins which have the same functions with LAMC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| extracellular matrix structural constituent | EFEMP2,COL27A1B,MATN1,IMPG2,FBLN1,COL27A1,TINAGL1,KAL1,COMP,FBN1 |
| glycosphingolipid binding | LAMA1,SELL,Il2,Cel,LAMB1,LYN,SELP |
Interacting Protein
LAMC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LAMC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LAMC1.
SNAPIN;SNX2;PDIA3;SRPK1;LAMA5;ATF7IP;CENPU;TANK;CCDC53;cona_canen;PHKG2;PYHIN1
Resources
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References
- Paez, MC; Matsuura, E; et al. Laminin-1 (LM-111) in preeclampsia and systemic lupus erythematosus. AUTOIMMUNITY 46:14-20(2013).
- Vafia, K; Groth, S; et al. Pathogenicity of Autoantibodies in Anti-p200 Pemphigoid. PLOS ONE 7:-(2012).
