KRT84
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Official Full Name
Keratin 84 -
Overview
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin is contained primarily in the filiform tongue papilla, among other hair keratins. -
Synonyms
KRT84;keratin 84;hHb4;Basic Hair Keratin K84;HB4;KRTHB4;K84;Hb-4;keratin-84;type-II keratin Kb24;type II hair keratin 4;keratin, hair, basic, 4;hard keratin, type II, 4;type II hair keratin Hb4;keratin, type II cuticular Hb4.
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KRT84-8860M | Recombinant Mouse KRT84 Protein | Mammalian Cell | Mouse | His |
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| KRT84-4831H | Recombinant Human KRT84 Protein, GST-tagged | Wheat Germ | Human | GST |
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| KRT84-4945M | Recombinant Mouse KRT84 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| KRT84-4945M-B | Recombinant Mouse KRT84 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| KRT84-5789HF | Recombinant Full Length Human KRT84 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 600 amino acids |
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| KRT84-880H | Recombinant Human KRT84 Protein, His-tagged | E.coli | Human | His |
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Involved Pathway
KRT84 involved in several pathways and played different roles in them. We selected most pathways KRT84 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT84 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
KRT84 has several biochemical functions, for example, structural constituent of epidermis,structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT84 itself. We selected most functions KRT84 had, and list some proteins which have the same functions with KRT84. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural molecule activity | CLDN12,SEPT7,JUP,MAP4,CDC42SE1,RLN3B,CLDN8,CLTA,LMNL3,MATR3 |
| structural constituent of epidermis | LOR,PKP1,KRT36 |
Interacting Protein
KRT84 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT84 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT84.
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References
- Chang, XT; Zhao, Y; et al. Screening Citrullinated Proteins in Synovial Tissues of Rheumatoid Arthritis Using 2-dimensional Western Blotting. JOURNAL OF RHEUMATOLOGY 40:219-227(2013).
