KRT75
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Official Full Name
keratin 75 -
Overview
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS). -
Synonyms
KRT75;keratin 75;K6hf;Keratin K75;PFB;K6HF;KB18;keratin, type II cytoskeletal 75;K75;CK-75;hK6hf;keratin-75;cytokeratin-75;type II keratin-18;cytokeratin type II;type II keratin-K6hf;type-II keratin Kb18;keratin-6 hair follicle
Recombinant Proteins
- Chicken
- Rat
- Mouse
- Human
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KRT75-1094C | Recombinant Chicken KRT75 | Mammalian Cell | Chicken | His |
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| KRT75-3330R | Recombinant Rat KRT75 Protein | Mammalian Cell | Rat | His |
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| KRT75-8850M | Recombinant Mouse KRT75 Protein | Mammalian Cell | Mouse | His |
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| KRT75-2986R | Recombinant Rat KRT75 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| KRT75-2986R-B | Recombinant Rat KRT75 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| KRT75-4839H | Recombinant Human KRT75 Protein, GST-tagged | Wheat Germ | Human | GST |
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| KRT75-4938M | Recombinant Mouse KRT75 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| KRT75-4938M-B | Recombinant Mouse KRT75 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| KRT75-6088HF | Recombinant Full Length Human KRT75 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 551 amino acids |
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Involved Pathway
KRT75 involved in several pathways and played different roles in them. We selected most pathways KRT75 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT75 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
KRT75 has several biochemical functions, for example, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT75 itself. We selected most functions KRT75 had, and list some proteins which have the same functions with KRT75. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural molecule activity | MAP7D2A,PLP1,LMNA,SPRR2F,EPB41L3A,CLDNG,SPRR1A,CLDN17,CLDN15,LELP1 |
Interacting Protein
KRT75 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT75 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT75.
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References
- Stockman, DL; Hornick, JL; et al. ERG and FLI1 protein expression in epithelioid sarcoma. MODERN PATHOLOGY 27:496-501(2014).
- Li, QX; Cui, WL; et al. Application of Immunohistochemistry in the Diagnosis of Small Round Blue-Cell Tumors of Soft Tissue. CLINICAL LABORATORY 60:1383-1392(2014).
