KNTC1
-
Official Full Name
kinetochore associated 1 -
Overview
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. Experimental evidence indicated that the encoded protein functioned in a similar manner to that of the Drosophila rough deal protein. -
Synonyms
KNTC1;kinetochore associated 1;kinetochore-associated protein 1;KIAA0166;ROD;rough deal homolog (Drosophila);HsROD;Rough Deal homolog, centromere/kinetochore protein;hRod;OTTHUMP00000236760
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KNTC1-8796M | Recombinant Mouse KNTC1 Protein | Mammalian Cell | Mouse | His |
|
|
| KNTC1-4894M | Recombinant Mouse KNTC1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| KNTC1-4894M-B | Recombinant Mouse KNTC1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
||
| KNTC1-4900H | Recombinant Human KNTC1 Protein, GST-tagged | Wheat Germ | Human | GST |
|
Involved Pathway
KNTC1 involved in several pathways and played different roles in them. We selected most pathways KNTC1 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,M Phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with KNTC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RHO GTPase Effectors | RTKN,PMF1,ZW10,NF2A,NCKAP1,BAIAP2,IQGAP3,LIN7B,SKA1,RHPN2 |
| Cell cycle | INCENP,MCM2,DIDO1,CCNB2,CSNK2A2,ESCO2,UIMC1,NCAPG,DYNC1I2,RAD1 |
| Mitotic Anaphase | SPDL1,SPC24,CENPO,RCC2,LEMD3,CENPP,CENPN,SPC25,NDC80,VRK1 |
| M Phase | ENSA,B9D2,SPDL1,ZWILCH,AHCTF1,RANGAP1B,ENSAA,CDCA5,NSL1,CENPQ |
| Cell Cycle, Mitotic | PDS5A,NCAPH2,MIS12,CEP78,NEDD1,ERCC6L,VRK2,CTDNEP1A,DYRK1A,FOXM1 |
| RHO GTPases Activate Formins | ZW10,MIS12,NSL1,FMNL2,EVL,DIAPH1,CCDC99,SGOL2,SKA2,ZWINT |
| Mitotic Prometaphase | WAPAL,ZWINT,MLF1IP,NDEL1B,CDCA8,SPC24,SKA1,DSN1,CENPC1,ZWILCH |
| Mitotic Metaphase and Anaphase | CENPE,ZWILCH,CENPK,MLF1IP,ANKLE2,CLIP1,CENPC1,NDC80,CENPI,NUF2 |
Protein Function
KNTC1 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by KNTC1 itself. We selected most functions KNTC1 had, and list some proteins which have the same functions with KNTC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | CFAP58,SYNGR2A,DEFA23,TMEM160,PDK3B,TMEM144,GRINAA,LPAL2,EMILIN1B,TECRL |
Interacting Protein
KNTC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KNTC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KNTC1.
Ywhah;Iqcb1
Resources
Related Services
Related Products
References
- Li, BC; Choulet, F; et al. Wheat centromeric retrotransposons: the new ones take a major role in centromeric structure. PLANT JOURNAL 73:952-965(2013).
- Huang, X; Wang, HL; et al. DYNLT3 Is Required for Chromosome Alignment During Mouse Oocyte Meiotic Maturation. REPRODUCTIVE SCIENCES 18:983-989(2011).
