KLHDC8B
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Official Full Name
kelch domain containing 8B -
Overview
This gene encodes a protein which forms a distinct beta-propeller protein structure of kelch domains allowing for protein-protein interactions. Mutations in this gene have been associated with Hodgkin lymphoma. -
Synonyms
KLHDC8B;kelch domain containing 8B;kelch domain-containing protein 8B;MGC35097;FLJ11302
Recombinant Proteins
- Rhesus macaque
- Rat
- Human
- Mouse
- Mammalian Cells
- E.coli
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
KLHDC8B involved in several pathways and played different roles in them. We selected most pathways KLHDC8B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KLHDC8B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
KLHDC8B has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by KLHDC8B itself. We selected most functions KLHDC8B had, and list some proteins which have the same functions with KLHDC8B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
KLHDC8B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLHDC8B here. Most of them are supplied by our site. Hope this information will be useful for your research of KLHDC8B.
Dlg4
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References
- Krem, MM; Luo, P; et al. The Kelch Protein KLHDC8B Guards against Mitotic Errors, Centrosomal Amplification, and Chromosomal Instability. JOURNAL OF BIOLOGICAL CHEMISTRY 287:39083-39093(2012).
- Saarinen, S; Vahteristo, P; et al. Analysis of KLHDC8B in familial nodular lymphocyte predominant Hodgkin lymphoma. BRITISH JOURNAL OF HAEMATOLOGY 154:413-415(2011).
