KIF17
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Official Full Name
kinesin family member 17 -
Overview
Kinesin-like protein KIF17 is a protein that in humans is encoded by the KIF17 gene.KIF17 and its close relative, C. elegans OSM-3,are members of the kinesin-2 family of plus-end directed microtubule-based motor proteins.In contrast to heterotrimeric kinesin-2 motors,however, KIF17 and OSM-3 form distinct homodimeric complexes.Homodimeric kinesin-2 has been implicated in the transport of NMDA receptors along dendrites for delivery to the dendritic membrane,whereas both heterotrimeric and homodimeric kinesin-2 motors function cooperatively in anterograde intraflagellar transport (IFT) and cilium biogenesis. -
Synonyms
KIF17;kinesin family member 17;kinesin-like protein KIF17;KIAA1405;KIF3 related motor protein;KIF3X;KIF17 variant protein;KIF17B;kinesin like protein KIF17;KIF3-related motor protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KIF17-360H | Recombinant Human KIF17, GST-tagged | E.coli | Human | GST | 1-351aa | |
| KIF17-3072H | Recombinant Human KIF17 protein, His-tagged | E.coli | Human | His | 754-1028 aa | |
| KIF17-4953HCL | Recombinant Human KIF17 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
KIF17 involved in several pathways and played different roles in them. We selected most pathways KIF17 participated on our site, such as Assembly of the primary cilium,Intraflagellar transport,Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Intraflagellar transport | WDR19,TTC21B,CLUAP1,DYF-1,TCTEX1D2,DYNLRB2,TTC30A1,DYNLRB1,TCTEX1D1,TNPO1 |
| Organelle biogenesis and maintenance | TMEM216,TCTN1,MRPL54,TRIP11,WDR19,TTC30A2,MRPL40,NPHP4,RABL5,CCDC123 |
| Assembly of the primary cilium | WDR34,NDE1,IFT20,CNGA2,IFT27,LZTFL1,B9D2,SETD6,PLK4,IFT43 |
Protein Function
KIF17 has several biochemical functions, for example, ATP binding,ATP-dependent microtubule motor activity, plus-end-directed,microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF17 itself. We selected most functions KIF17 had, and list some proteins which have the same functions with KIF17. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP-dependent microtubule motor activity, plus-end-directed | KIF5C,KIF14,KIF18A,KIF5A,KIF3A,KIF18B,KIF5AA,KIF5B,KIF1C,KIF16B |
| microtubule binding | NME8,UXT,MAP2,KATNAL2,KLC3,SGIP1,EML2,NDEL1,KIF22,GAS2L1 |
| ATP binding | NIM1,TSSK2,MLH3,LANCL2,XRCC2,YTHDC2,TOP2A,GSK3AB,SLK,SIK2 |
Interacting Protein
KIF17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF17 here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF17.
q5nig6_fratt;GFI1B;q9wmx2-pro_0000037548
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References
- Seog, DH; Han, J; et al. Sorting nexin 17 interacts directly with kinesin superfamily KIF1B beta protein. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY 12:199-204(2008).
