KIF11
-
Official Full Name
kinesin family member 11 -
Overview
This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. [provided by RefSeq, Jul 2008] -
Synonyms
KIF11;kinesin family member 11;EG5;HKSP;KNSL1;MCLMR;TRIP5;kinesin-like protein KIF11;TRIP-5;kinesin-like protein 1;TR-interacting protein 5;kinesin-like spindle protein HKSP;kinesin-related motor protein Eg5;thyroid receptor-interacting protein 5
Recombinant Proteins
- Human
- Chicken
- Mouse
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- DDK&Myc
- Avi&Fc&His
- Flag
Involved Pathway
KIF11 involved in several pathways and played different roles in them. We selected most pathways KIF11 participated on our site, such as Adaptive Immune System,Factors involved in megakaryocyte development and platelet production,Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MHC class II antigen presentation | MGC174857,CTSLL,KIF22,FAM49BA,KIF15,AP1S3A,RACGAP1,CTSC,KLC3,MGC174155 |
| Hemostasis | KIF9,GNA13,DOCK6,KCNMA1,AASS,ANGPT2A,KIF3B,KLC3,MAFF,G6b |
| Factors involved in megakaryocyte development and platelet production | HBD,KIFAP3,KDM1A,HBBE3,DOCK11,ZFPM1,OSTN,KIF9,MAFGA,HBBE2 |
| Adaptive Immune System | TREML4,IFI30,KIF4,IGHM,TRIM9,AP1S3A,SIGLEC8,ARIH2,UBE2F,HUWE1 |
| Immune System | CD300E,FCN1,ARIH1,NPEPPS,TRIM9,IRF9,ASB7,MKRN1,DEFB104A,SOCS3A |
| Kinesins | RACGAP1,KIF9,KIF2B,KIF5A,KIF26A,CENPE,KIF2C,KIF4,KIF15,KIF3C |
Protein Function
KIF11 has several biochemical functions, for example, ATP binding,ATP-dependent microtubule motor activity, plus-end-directed,microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF11 itself. We selected most functions KIF11 had, and list some proteins which have the same functions with KIF11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | MVD,RTCD1,CAMK4,KLHL8,OPLAH,MYHZ1.1,CSNK2A2,DCLK1,TTLL2,CKBB |
| protein complex binding | LEPRE1,LCA5,LCK,FLCN,CPD,HADHA,HCLS1,LRRC16A,UFD1L,CYFIP1 |
| protein kinase binding | NEK9,ATF2,SPRED1,KIF20A,FBXW5,C10orf46,PGAM1,CD24,RFFL,DUSP3 |
| microtubule binding | PRC1A,KIF22,MAPT,CDK5RAP2,KIFC1,KIF17,MAP1S,TRIM54,KIF5A,NEFH |
| ATP-dependent microtubule motor activity, plus-end-directed | KIF1B,KIF5B,KIF19,KIF16B,KIF17,KIF5C,KIF20B,KIF5AA,KIF14,KIF18A |
| microtubule motor activity | KLC3,KIFC2,KIF27,KIF12,KIF3CB,SMC3,DNAH9,KIF23,KIF2C,DYNC1H1 |
Interacting Protein
KIF11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF11 here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF11.
IKBKE;TNIP3;ILVBL;b4dt77_human;b4e2x3_human;pi3p;MRPL27;MAP4;KIAA0922;H3F3B;MYO1C;SUV39H1;MED14;HIST1H2BK;DUSP11;PEX14;AP2A2
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