KIAA0319
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Official Full Name
KIAA0319 -
Overview
This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in this gene are associated with dyslexia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. -
Synonyms
KIAA0319;dyslexia-associated protein KIAA0319;dyslexia susceptibility 2;DYX2;DYLX2;MGC176717
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| KIAA0319-1245H | Recombinant Human KIAA0319 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| KIAA0319-1245H-B | Recombinant Human KIAA0319 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| KIAA0319-1288HFL | Recombinant Full Length Human KIAA0319 Protein, C-Flag-tagged | Mammalian cells | Human | Flag | Full L. |
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| KIAA0319-402H | Recombinant Human KIAA0319 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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Involved Pathway
KIAA0319 involved in several pathways and played different roles in them. We selected most pathways KIAA0319 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KIAA0319 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
KIAA0319 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by KIAA0319 itself. We selected most functions KIAA0319 had, and list some proteins which have the same functions with KIAA0319. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
KIAA0319 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIAA0319 here. Most of them are supplied by our site. Hope this information will be useful for your research of KIAA0319.
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References
- Poon, MW; Tsang, WH; et al. Distribution of Kiaa0319-like immunoreactivity in the adult mouse brain - a novel protein encoded by the putative dyslexia susceptibility gene KIAA0319-like. HISTOLOGY AND HISTOPATHOLOGY 26:953-963(2011).
- Levecque, C; Velayos-Baeza, A; et al. The dyslexia-associated protein KIAA0319 interacts with adaptor protein 2 and follows the classical clathrin-mediated endocytosis pathway. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 297:C160-C168(2009).
