KCNV2
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Official Full Name
potassium channel, subfamily V, member 2 -
Overview
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a silent subunit, and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues. -
Synonyms
KCNV2;potassium channel, subfamily V, member 2;potassium voltage-gated channel subfamily V member 2;Kv8.2;voltage-gated potassium channel subunit Kv8.2;RCD3B;KV11.1;MGC120515
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KCNV2-8557M | Recombinant Mouse KCNV2 Protein | Mammalian Cells | Mouse | His |
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| KCNV2-4762M | Recombinant Mouse KCNV2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| KCNV2-4762M-B | Recombinant Mouse KCNV2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| RFL34788HF | Recombinant Full Length Human Potassium Voltage-Gated Channel Subfamily V Member 2(Kcnv2) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-545) |
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| RFL8650MF | Recombinant Full Length Mouse Potassium Voltage-Gated Channel Subfamily V Member 2(Kcnv2) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length (1-562) |
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Involved Pathway
KCNV2 involved in several pathways and played different roles in them. We selected most pathways KCNV2 participated on our site, such as Neuronal System,Potassium Channels,Voltage gated Potassium channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNV2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Voltage gated Potassium channels | KCNG3,KCNG1,KCNAB1,KCNF1,KCNC1B,KCNS2,KCNC3A,KCNC1,KCNQ2,KCNH2A |
| Potassium Channels | KCNN4,ABCC9,KCNJ1A.1,KCNJ1A.2,KCNH1,KCNMB1,KCNN1B,KCNA2,KCNAB2,KCNH5 |
| Neuronal System | KCNC1,PICK1,CHRNE,SLC1A2A,KCNV1,RERG,GLS2B,CHRND,KCNA6A,Apba1 |
Protein Function
KCNV2 has several biochemical functions, for example, delayed rectifier potassium channel activity,ion channel activity,potassium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNV2 itself. We selected most functions KCNV2 had, and list some proteins which have the same functions with KCNV2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| potassium channel activity | KCNC2,KCNS3A,KCNH5,KCNK5A,FXYD4,KCNH6A,KCNC1A,KCNK7,AQP1,KCNK15 |
| voltage-gated ion channel activity | KCNJ1A.6,CACNG2A,SCN4AB,KCNA2B,CACNA1DA,SCN4AA,GPR89,CLCN3,CACNG1A,CACNG8A |
| ion channel activity | KCNV2B,CNGA4,GRIA4B,KCNF1A,KCNC3A,CNGA5,TRPM1B,SCN12AB,TRPV2,TRPM5 |
| delayed rectifier potassium channel activity | KCNC1,KCNG1,KCNA2B,KCNV1,KCNB1,KCNA6A,KCNG4A,KCNQ4,KCNV2B,KCNC1A |
| voltage-gated potassium channel activity | KCNAB2B,HCN4,KCNH2,KCNK9,KCNA4,KCNS3A,KCNG4A,KCNMA1A,KCNH6A,HCN2 |
Interacting Protein
KCNV2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNV2 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNV2.
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References
- VEH, RW; LICHTINGHAGEN, R; et al. IMMUNOHISTOCHEMICAL LOCALIZATION OF 5 MEMBERS OF THE KV1 CHANNEL SUBUNITS - CONTRASTING SUBCELLULAR LOCATIONS AND NEURON-SPECIFIC CO-LOCALIZATIONS IN RAT-BRAIN. EUROPEAN JOURNAL OF NEUROSCIENCE 7:2189-2205(1995).
