KCNK6
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Official Full Name
potassium inwardly-rectifying channel, subfamily K, member 6 -
Overview
Potassium channel subfamily K member 6 is a protein that in humans is encoded by the KCNK6 gene. -
Synonyms
KCNK6;potassium inwardly-rectifying channel, subfamily K, member 6;D7Ertd764e;KCNK8;TWIK 2;TWIK2;FLJ12282;Inward rectifying potassium channel protein TWIK 2;K2p6.1;K2P6.1 potassium channel;Potassium channel, subfamily K, member 6 (TWIK 2);Potassium channel, subfamily K, member 6;TOSS;TWIK 2 two pore domain K+ channel;TWIK originated sodium similarity sequence;TWIK-2 two-pore-domain K+ channel
Recombinant Proteins
- Zebrafish
- Human
- Mouse
- Mammalian Cell
- HEK293
- HEK293T
- E.coli expression system
- His
- Non
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KCNK6-3214Z | Recombinant Zebrafish KCNK6 | Mammalian Cell | Zebrafish | His |
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| KCNK6-5032HCL | Recombinant Human KCNK6 293 Cell Lysate | HEK293 | Human | Non |
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| KCNK6-229HCL | Recombinant Human KCNK6 Lysate | HEK293 | Human | Myc&DDK |
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| Kcnk6-3661M | Recombinant Mouse Kcnk6 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| KCNK6-5270H | Recombinant Human KCNK6 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Kcnk6-83M | Recombinant Mouse Kcnk6 protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| KCNK6-909H | Recombinant Human KCNK6 protein, Myc/DDK-tagged | HEK293 | Human | Myc&DDK |
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| RFL35864HF | Recombinant Full Length Human Potassium Channel Subfamily K Member 6(Kcnk6) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-313) |
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Involved Pathway
KCNK6 involved in several pathways and played different roles in them. We selected most pathways KCNK6 participated on our site, such as Neuronal System,Potassium Channels,Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK), which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNK6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuronal System | KCNMB1,KCNS3A,KCNK1B,SLC1A7B,GJA10,KCNH5A,SYT1A,KCNF1,CACNB4B,KCNK10B |
| Potassium Channels | KCND1,KCNQ2A,HCN4,KCNQ3,KCNH5A,KCND2,KCNK2B,KCNH6,KCNN1B,KCNK13B |
| Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) | KCNK1A,KCNK7,KCNK1,KCNK1B |
| Tandem pore domain potassium channels | KCNK16,KCNK2,KCNK18,KCNK13A,KCNK1B,KCNK7,KCNK4,KCNK13B,KCNK2B,KCNK1 |
Protein Function
KCNK6 has several biochemical functions, for example, inward rectifier potassium channel activity,potassium ion leak channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNK6 itself. We selected most functions KCNK6 had, and list some proteins which have the same functions with KCNK6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| potassium ion leak channel activity | TMEM175,KCNK15,KCNK9,KCNK16,KCNK3A,KCNK2,DDX1,KCNK1A,KCNK13A,KCNK18 |
| inward rectifier potassium channel activity | KCNJ13,KCNH2,KCNJ1A.3,KCNJ16,KCNJ14,KCNJ8,KCNJ1A.1,KCNJ2A,KCNJ1A.6,KCNJ1 |
Interacting Protein
KCNK6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNK6 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNK6.
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References
- Langford, DJ; Paul, SM; et al. Variations in potassium channel genes are associated with distinct trajectories of persistent breast pain after breast cancer surgery. PAIN 156:371-380(2015).
- Delaney, JT; Muhammad, R; et al. A KCNJ8 mutation associated with early repolarization and atrial fibrillation. EUROPACE 14:1428-1432(2012).
