KCNH7
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Official Full Name
potassium voltage-gated channel, subfamily H (eag-related), member 7 -
Overview
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. -
Synonyms
KCNH7;potassium voltage-gated channel, subfamily H (eag-related), member 7;potassium voltage-gated channel subfamily H member 7;erg3;HERG3;Kv11.3;ERG-3;eag related protein 3;eag-related protein 3;ether-a-go-go-related protein 3;potassium channel
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KCNH7-3188R | Recombinant Rat KCNH7 Protein | Mammalian Cells | Rat | His |
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| KCNH7-8504M | Recombinant Mouse KCNH7 Protein | Mammalian Cells | Mouse | His |
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| KCNH7-2844R | Recombinant Rat KCNH7 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| KCNH7-2844R-B | Recombinant Rat KCNH7 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| KCNH7-4733M | Recombinant Mouse KCNH7 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| KCNH7-4733M-B | Recombinant Mouse KCNH7 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
KCNH7 involved in several pathways and played different roles in them. We selected most pathways KCNH7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNH7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
KCNH7 has several biochemical functions, for example, DNA binding,metal ion binding,nucleic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNH7 itself. We selected most functions KCNH7 had, and list some proteins which have the same functions with KCNH7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | CYP2K17,CALM4,STAC,MAT2AA,ZSCAN4,KDM6BB,LATS2,SALL1,NPEPPS,GMIP |
| protein binding | GLI1,CNBP,ARL6IP5,EGR1,ELMOD3,ALAS1,CXXC11,RPS6KA5,CDA,TAX1BP3 |
| DNA binding | ZBTB8A,TCEA1,SIX7,BEND5,ING2,HIST1H2AL,ZFP64,GCM2,VDR,FOXG1B |
| nucleic acid binding | ZBTB16A,ZFP41,ZNF292A,ZNF503,EGR2B,EWSR1B,ANG4,TSEN34,RBM20,SYNCRIPL |
Interacting Protein
KCNH7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNH7 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNH7.
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References
- Zurawek, M; Fichna, M; et al. Cumulative effect of IFIH1 variants and increased gene expression associated with type 1 diabetes. DIABETES RESEARCH AND CLINICAL PRACTICE 107:259-266(2015).
- Varzari, A; Bruch, K; et al. Analysis of polymorphisms in RIG-I-like receptor genes in German multiple sclerosis patients. JOURNAL OF NEUROIMMUNOLOGY 277:140-144(2014).
