KCNA5
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Official Full Name
potassium voltage-gated channel, shaker-related subfamily, member 5 -
Synonyms
KCNA5;potassium voltage-gated channel, shaker-related subfamily, member 5;potassium voltage-gated channel subfamily A member 5;HK2;HPCN1;Kv1.5;potassium channel 1;cardiac potassium channel;potassium channel protein;voltage-gated potassium channel
Recombinant Proteins
- Human
- Rat
- Mouse
- Oryctolagus cuniculus
- Mus musculus
- Mustela putorius furo (European domestic ferret) (Mustela furo)
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Avi
- Fc
Involved Pathway
KCNA5 involved in several pathways and played different roles in them. We selected most pathways KCNA5 participated on our site, such as Neuronal System,Potassium Channels,Voltage gated Potassium channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Voltage gated Potassium channels | KCNC2,KCNAB2B,KCNF1,KCNH1A,KCNH5A,KCNS3,KCNV1,KCNC1B,KCNH5,KCNAB3 |
| Potassium Channels | KCNN2,KCNV1,KCNQ2,KCNQ1,KCNG3,KCNK13A,KCNK1,KCNJ14,KCNK3A,KCNB2 |
| Neuronal System | PPFIA2,LIN7A,SLC6A12,KCNN2,SNAP25A,KCNK13A,SLC17A7A,ARL6IP5B,CHRNB4,SYN1 |
Protein Function
KCNA5 has several biochemical functions, for example, alpha-actinin binding,delayed rectifier potassium channel activity,outward rectifier potassium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNA5 itself. We selected most functions KCNA5 had, and list some proteins which have the same functions with KCNA5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| outward rectifier potassium channel activity | KCNK2,KCNQ1,KCNK2B,REST,KCNB1,KCNK18,KCNK5B,KCNK1A |
| potassium channel inhibitor activity | ENSA,KCNK2,CAV3,RASA1,NEDD4L,PTI |
| alpha-actinin binding | MYOT,LRRC10,XIRP2,ALMS1,PKD2L1,ADORA2A,DAG1,PPARG,RARA,MAGI1 |
| protein kinase binding | CCNL1,DLG1,AGAP2,DBF4B,SPDYB,CNTLN,RHEB,NPM1,CHRNA7,ELAVL1 |
| voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization | KCNQ1 |
| receptor binding | TNFSF15,PTK2,RASA1,ASIP,LAMA4,CADM3,FLT3LG,HIST2H3C2,Ar,ANGPTL1 |
| delayed rectifier potassium channel activity | KCNC3B,KCNV2,KCNQ5,KCNA7,KCNA6,KCNC3A,KCNC1,KCNV1,KCNC1A,KCNS3 |
| protein binding | ID2,GALNT3,ITGA2B,PUM2,RGP1,PIK3R6,PRF1,NOXA1,IFIT2,LINC01588 |
| scaffold protein binding | CACNA1G,SCN5A,KCNH2,TREM1,MAPK3,NCK2,CAV2,DLG4,CRIPT,KRT18 |
Interacting Protein
KCNA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNA5.
ACTN2;HSP90AB1
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References
- VEH, RW; LICHTINGHAGEN, R; et al. IMMUNOHISTOCHEMICAL LOCALIZATION OF 5 MEMBERS OF THE KV1 CHANNEL SUBUNITS - CONTRASTING SUBCELLULAR LOCATIONS AND NEURON-SPECIFIC CO-LOCALIZATIONS IN RAT-BRAIN. EUROPEAN JOURNAL OF NEUROSCIENCE 7:2189-2205(1995).
