KAL1
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Official Full Name
Kallmann syndrome 1 sequence -
Overview
Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity. -
Synonyms
KAL1;Kallmann syndrome 1 sequence;ADMLX, KAL;anosmin-1;anosmin 1;KALIG 1;KAL;Adhesion molecule-like X-linked;ADMLX;HHA;KALIG1;Kallmann syndrome 1 sequence (anosmin 1);Kallmann syndrome interval gene 1;Kallmann syndrome protein;KALM;KALM_HUMAN;KMS;OTTHUMP00000022873;Kallmann syndrome-1 sequence (anosmin-1);KALIG-1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KAL1-29684TH | Recombinant Human KAL1 | Wheat Germ | Human | Non | 110 amino acids |
|
| KAL1-5256H | Recombinant Human KAL1 Protein, His-tagged | E.coli | Human | His | 384-680 a.a. |
|
| KAL1-6975C | Recombinant Chicken KAL1 | Mammalian Cells | Chicken | His |
|
|
| KAL1-5093HCL | Recombinant Human KAL1 293 Cell Lysate | HEK293 | Human | Non |
|
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| KAL1-563H | Recombinant Human KAL1 protein, His-tagged | E.coli | Human | His | 380-614aa |
|
Involved Pathway
KAL1 involved in several pathways and played different roles in them. We selected most pathways KAL1 participated on our site, such as FGFR1 ligand binding and activation,FGFR1c ligand binding and activation,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling by FGFR1 | KAL1A |
| Signal Transduction | CCNT2B,LPAR2A,GPR55A,CALCB,RHOF,ABHD6B,ABHD12,ACVR1C,NMT1A,NPSR1 |
| Signaling by FGFR | FGFBP3,FGFBP2,FGFBP1,KAL1A |
| FGFR1c ligand binding and activation | KAL1A |
| FGFR1 ligand binding and activation | KAL1A |
Protein Function
KAL1 has several biochemical functions, for example, extracellular matrix structural constituent,heparin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KAL1 itself. We selected most functions KAL1 had, and list some proteins which have the same functions with KAL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| heparin binding | FGFBP1,FBLN7,CCL23,ABP1,FMOD,LRPAP1,VEGFAA,CXCL6,NAV2,ECM2 |
| protein binding | FOXO3,NACA,MFAP4,TREML1,FAM82A2,ICAM4,BCL2A1,RABGAP1,ATXN1,XPO7 |
| serine-type endopeptidase inhibitor activity | SERPIND1,SERPINB2,SERPINA11,SERPINH1,SPOCK1,SERPINB7,SERPINB9,SPINK3,SERPINB1L4,WFDC6 |
| extracellular matrix structural constituent | FBLN2,PXDN,LAMA4,MFAP5,COL1A1A,MATN1,COL2A1A,BGN,IMPG2,COL4A6 |
Interacting Protein
KAL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KAL1.
FGFR1;heparin;FGFR2;FGF2
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