IWS1
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Official Full Name
IWS1 homolog -
Overview
Various steps in gene expression, such as mRNA processing, surveillance, export, and synthesis are coupled to transcription elongation. The C-terminal domain (CTD) of the large subunit of RNA polymerase II plays an important role in the integration of the -
Synonyms
IWS1;IWS1 homolog (S. cerevisiae);protein IWS1 homolog;DKFZp761G0123;FLJ10006;FLJ14655;FLJ32319;IWS1-like protein;interacts with Spt6;MGC126375;MGC126376
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IWS1-0395H | Recombinant Human IWS1 protein, His-tagged | E.coli | Human | His | 523-819 aa | |
| IWS1-3131R | Recombinant Rat IWS1 Protein | Mammalian Cells | Rat | His |
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| IWS1-8400M | Recombinant Mouse IWS1 Protein | Mammalian Cells | Mouse | His |
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| IWS1-2787R | Recombinant Rat IWS1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| IWS1-2787R-B | Recombinant Rat IWS1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| IWS1-4662M | Recombinant Mouse IWS1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| IWS1-4662M-B | Recombinant Mouse IWS1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| IWS1-4939H | Recombinant Human IWS1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| IWS1-5852HF | Recombinant Full Length Human IWS1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 819 amino acids |
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Involved Pathway
IWS1 involved in several pathways and played different roles in them. We selected most pathways IWS1 participated on our site, such as Proteasome Degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with IWS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Proteasome degradation | FBXO17,ARIH2,ASB4,DZIP3,RNF14,UFL1,HECTD3,UBE2V1,WSB1,RBCK1 |
Protein Function
IWS1 has several biochemical functions, for example, peptidase activity,protein binding,ubiquitin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IWS1 itself. We selected most functions IWS1 had, and list some proteins which have the same functions with IWS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin binding | TRP53INP2,KIF18A,BRAP,OTUB1,FAF1,USP25,TOM1L1,UBR5,OTUB2,RNF31 |
| ubiquitin-specific protease activity | UFD1L,CYLD,USP25,USP7,FMNL3,OTUB1B,OTUD5B,USP47,USP5,USP22 |
| peptidase activity | GZMF,HE1B,KLK5,ZRANB1B,PRSS48,REN2,USP25,TMPRSS13A,BMP1,PRSS30 |
| protein binding | GNAI2,SF3A2,NCOR1,DPEP1,ARMC8,OTULIN,HSFY1,NME5,HAT1,TECPR1 |
Interacting Protein
IWS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IWS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IWS1.
Ywhae
Resources
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References
- Gerard, A; Segeral, E; et al. The Integrase Cofactor LEDGF/p75 Associates with Iws1 and Spt6 for Postintegration Silencing of HIV-1 Gene Expression in Latently Infected Cells. CELL HOST & MICROBE 17:107-117(2015).
- Wang, XL; Chen, JN; et al. Histone Lysine Methyltransferase SDG8 Is Involved in Brassinosteroid-Regulated Gene Expression in Arabidopsis thaliana. MOLECULAR PLANT 7:1303-1315(2014).
