ITGB5
-
Official Full Name
integrin, beta 5 -
Overview
Integrin beta-5 is a protein that in humans is encoded by the ITGB5 gene. -
Synonyms
ITGB5;integrin, beta 5;integrin beta-5;FLJ26658
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Chicken
- Mouse
- Mus musculus
- Bovine
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Myc&DDK
- GST
Involved Pathway
ITGB5 involved in several pathways and played different roles in them. We selected most pathways ITGB5 participated on our site, such as Phagosome,PIK-Akt signaling pathway,Focal adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITGB5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Phagosome | CALRL2,HLA-DRB4,TUBB5,BLB2,TUBA3C,BMA1,ITGB1A,ATP6V0C,PIKFYVE,TUBA1A |
| ECM-receptor interaction | COL1A1,SDC1,COL4A1,COL27A1B,COL6A6,ITGA2B,ITGB6,SPP1,LAMC1,THBS1 |
| Dilated cardiomyopathy | Adcy4,ITGA5,ACTB,TNNI3,CACNA2D4,ITGA6,CACNG7,CACNG4,ITGA2B,GNAS |
| Hypertrophic cardiomyopathy (HCM) | DAG1,RYR2,SGCA,TNF,TPM1,MYL3,ITGA10,CACNB3,ATP2A2,TGFB1 |
| Regulation of Actin Cytoskeleton | FGF13B,FGF8,PIP4K2B,PIKFYVE,KRAS,VAV3B,PFN2L,SLC9A1,PIP5K1BA,RAF1A |
| PIK-Akt signaling pathway | FGF9,COL4A1,HSP90AB1,PPP2R5D,Fgf15,MLST8,IFNA2,GNG8,KLK1B4,PPP2R2C |
| Focal adhesion | ITGA6,MAPK8B,GRB2,SHC3,LAMB2,PDGFD,RAC3A,RAPGEF1B,COL27A1B,COL6A4 |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | PKP2,ATP2A2,CACNA2D1,ITGB3,CACNA2D4,LAMA2,ITGA9,ACTB,CTNNA1,TCF7L2 |
| Proteoglycans in cancer | TRP53,VEGFA,HSPB2,TLR2,FAS,SMO,RRAS,ITGAV,FGF2,ARAF |
Protein Function
ITGB5 has several biochemical functions, for example, integrin binding,protein binding,virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ITGB5 itself. We selected most functions ITGB5 had, and list some proteins which have the same functions with ITGB5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| virus receptor activity | SLC1A5,HSPA1B,ACE2,ANPEP,HLA-DRB1,SCARB2,ITGAV,PVRL4,GPR172B,CLEC5A |
| protein binding | Arid4b,WAPAL,TBX18,CACNA1SB,HRK,ZMAT3,NAMPT,BLZF1,MEIOB,TIPRL |
| integrin binding | ACTN3,ICAM1,Npnt,ITGA3,TSPAN8,ACTN4,PPAP2B,TGFBI,CYR61,AMICA1 |
Interacting Protein
ITGB5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITGB5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITGB5.
FRMD5;ANGPTL4;Myo7a;MYO10;ITGAV;Tln1
Resources
Related Services
Related Products
References
