ISX
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Official Full Name
intestine-specific homeobox -
Overview
Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the RAXLX homeobox gene family. -
Synonyms
ISX;intestine-specific homeobox;RAXLX;DKFZp781N2395;MGC138417;OTTHUMP00000028558;Pancreas intestine homeodomain transcription factor;Pix 1;RAX like homeobox;RAX-like homeobox;pancreas-intestine homeodomain transcription factor;Pix-1
Recombinant Proteins
- Rhesus macaque
- Mouse
- Human
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- E.coli
- His
- His&Fc&Avi
- GST
- His&SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ISX-2310R | Recombinant Rhesus monkey ISX Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| ISX-8338M | Recombinant Mouse ISX Protein | Mammalian Cells | Mouse | His |
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| ISX-2131R | Recombinant Rhesus Macaque ISX Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| ISX-2131R-B | Recombinant Rhesus Macaque ISX Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| ISX-4628M | Recombinant Mouse ISX Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ISX-4628M-B | Recombinant Mouse ISX Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| ISX-5008H | Recombinant Human ISX Protein, GST-tagged | Wheat Germ | Human | GST |
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| ISX-5770HF | Recombinant Full Length Human ISX Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 245 amino acids |
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| ISX-587H | Recombinant Human ISX Protein (1-245 aa), His-SUMO-tagged | E.coli | Human | His&SUMO | 1-245 aa |
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Involved Pathway
ISX involved in several pathways and played different roles in them. We selected most pathways ISX participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ISX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
ISX has several biochemical functions, for example, DNA binding,sequence-specific DNA binding,transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ISX itself. We selected most functions ISX had, and list some proteins which have the same functions with ISX. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | ATF7,GRHL2,POU2F1B,FOXO1B,HOXB9,PTF1A,FOXJ3,MEF2A,TFCP2L1,KLF5 |
| DNA binding | KLF7,BARX2,POU3F3,AKNA,ZBTB17,ZFP667,AGFG1,POLR2EB,MLLT1,SOX1 |
| transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding | HOXD9,ETV6,DMBX1,BCL6,ETV7,MNT,MSX1,BCL6A,E2F7,ETV3 |
Interacting Protein
ISX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ISX here. Most of them are supplied by our site. Hope this information will be useful for your research of ISX.
Resources
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References
- PINKERTON, PH; COOVADIA, AS; et al. DELAYED TRANSFUSION REACTIONS FOLLOWING ANTIBODY SCREENING (AS) AND IMMEDIATE SPIN CROSS-MATCHING (ISX). TRANSFUSION 32:S27-S27(1992).
