IST1

  • Official Full Name

    increased sodium tolerance 1 homolog (yeast)
  • Overview

    This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Synonyms

    MGC117220;IST1;increased sodium tolerance-1;Putative MAPK-activating protein PM28;IST1 homolog;hIST1;KIAA0174;OTTHUMP00000174931;OTTHUMP00000174932;OTTHUMP00000238707;OTTHUMP00000238709;increased sodium tolerance 1 homolog (yeast)

Recombinant Proteins

  • Human
  • Zebrafish
  • Rat
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
IST1-13789H Recombinant Human IST1, GST-tagged E.coli Human GST 1-364a.a.
IST1-11864Z Recombinant Zebrafish IST1 Mammalian Cells Zebrafish His
IST1-3107R Recombinant Rat IST1 Protein Mammalian Cells Rat His
IST1-62H Recombinant Human IST1 protein, His-tagged E.coli Human His 350aa(including fusion tag)
IST1-8337M Recombinant Mouse IST1 Protein Mammalian Cells Mouse His
IST1-358HCL Recombinant Human IST1 lysate HEK293 Human Non
IST1-2763R Recombinant Rat IST1 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
IST1-2763R-B Recombinant Rat IST1 Protein Pre-coupled Magnetic Beads HEK293 Rat
IST1-4627M Recombinant Mouse IST1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
IST1-4627M-B Recombinant Mouse IST1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
IST1-5009H Recombinant Human IST1 Protein, GST-tagged Wheat Germ Human GST
IST1-5769HF Recombinant Full Length Human IST1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 366 amino acids

    Involved Pathway

    IST1 involved in several pathways and played different roles in them. We selected most pathways IST1 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with IST1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Endocytosis ADRB2A,STAM2,CLINT1A,ERBB3A,VPS36,SNX5,SH3GLB1,IL2RG,CXCR4,SH3GLB1A

    Protein Function

    IST1 has several biochemical functions, for example, MIT domain binding,protein binding,protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IST1 itself. We selected most functions IST1 had, and list some proteins which have the same functions with IST1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CASP9,ENSA,MED14,SPSB2,RACGAP1,FAM117B,TRAF7,UBE3A,TRAK1,ACD
    protein domain specific binding SFN,HIST2H4,ARHGEF4,E2F4,CA,YWHABA,ATP1A1,HIST1H4L,ERCC1,YWHABB
    protein complex binding RANBP2,DLG4,BAX,KLHL8,RPAIN,CDKN1A,VHLL,LAMB3,ANKRD54,CALCA

    Interacting Protein

    IST1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IST1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IST1.

    CAPN7;APEH;CAPN7;UBQLN1;ATXN1;q7ard3_yerpe;pi3p

    Resources

    References

    • Shao, Q; Han, N; et al. SsHKT1;1 is a potassium transporter of the C-3 halophyte Suaeda salsa that is involved in salt tolerance. FUNCTIONAL PLANT BIOLOGY 41:790-802(2014).
    • Gasparic, MB; Lenassi, M; et al. Insertion of a Specific Fungal 3 '-phosphoadenosine-5 '-phosphatase Motif into a Plant Homologue Improves Halotolerance and Drought Tolerance of Plants. PLOS ONE 8:-(2013).

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