IRX1

  • Official Full Name

    iroquois homeobox 1
  • Overview

    IRX1 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.
  • Synonyms

    IRX1;iroquois homeobox 1;iroquois-class homeodomain protein IRX-1;IRX 5;Iroquois Homeobox Protein 1;IRXA1;OTTHUMP00000220489;homeodomain protein IRXA1;IRX-5
Cat.# Product name Source (Host) Species Tag Protein Length Price
IRX1-2224C Recombinant Chicken IRX1 Mammalian Cells Chicken His
IRX1-8317M Recombinant Mouse IRX1 Protein Mammalian Cells Mouse His
IRX1-4613M Recombinant Mouse IRX1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
IRX1-4613M-B Recombinant Mouse IRX1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
IRX1-5027H Recombinant Human IRX1 Protein, GST-tagged Wheat Germ Human GST
IRX1-5748HF Recombinant Full Length Human IRX1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 480 amino acids

    Involved Pathway

    IRX1 involved in several pathways and played different roles in them. We selected most pathways IRX1 participated on our site, such as Cytokine-cytokine receptor interaction,Jak-STAT signaling pathway,Type III interferon signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with IRX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Type III interferon signaling IL10RB,IL28RA
    Jak-STAT signaling pathway Il2,CISHB,IL12A,IL9R,Il4ra,AOX1,IL22RA1,STAT2,FHL1,IL10RB
    Cytokine-cytokine receptor interaction LTBR,CCL21,EDAR,FASLG,ACKR3B,TNFRSF4,CCR8,CXCR1,IFNA2,IFNA1

    Protein Function

    IRX1 has several biochemical functions, for example, cytokine receptor activity,contributes_to cytokine receptor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IRX1 itself. We selected most functions IRX1 had, and list some proteins which have the same functions with IRX1. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to cytokine receptor activity CD44,IL28RA
    protein binding TICAM1,SLC39A7,FCER1G,BMF,GLE1,RBMY1B,SNX32,GABRG2,HOXB6,KCNA5
    cytokine receptor activity IL20RA,CRFB6,CRFB15,GHR,LIFRA,IL2RGA,PRLRA,CSF3R,CRFB17,IL1RL1

    Interacting Protein

    IRX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IRX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IRX1.

    Resources

    References

    • Persson, S; Caffall, KH; et al. The Arabidopsis irregular xylem8 mutant is deficient in glucuronoxylan and homogalacturonan, which are essential for secondary cell wall integrity. PLANT CELL 19:237-255(2007).
    • Diet, A; Link, B; et al. The Arabidopsis root hair cell wall formation mutant lrx1 is suppressed by mutations in the RHM1 gene encoding a UDP-L-rhamnose synthase. PLANT CELL 18:1630-1641(2006).

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