IRF2BP2
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Official Full Name
interferon regulatory factor 2 binding protein 2 -
Overview
This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding distinct isoforms. -
Synonyms
IRF2BP2;interferon regulatory factor 2 binding protein 2;interferon regulatory factor 2-binding protein 2;IRF 2BP2;IRF-2-binding protein 2;MGC72189
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IRF2BP2-8299M | Recombinant Mouse IRF2BP2 Protein | Mammalian Cells | Mouse | His |
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| IRF2BP2-4601M | Recombinant Mouse IRF2BP2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| IRF2BP2-4601M-B | Recombinant Mouse IRF2BP2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
IRF2BP2 involved in several pathways and played different roles in them. We selected most pathways IRF2BP2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IRF2BP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
IRF2BP2 has several biochemical functions, for example, metal ion binding,transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IRF2BP2 itself. We selected most functions IRF2BP2 had, and list some proteins which have the same functions with IRF2BP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription corepressor activity | NR0B2A,LIMD1,SSX3,TSG101,MSC,BCOR,ID4,ATN1,CDYL,YY1 |
| metal ion binding | PPM1F,GRIN2A,ZFP161,ZC3H15,ZCCHC16,ZFP553,POLR3A,CCDC71L,CDK15,CH25HL2 |
Interacting Protein
IRF2BP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IRF2BP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IRF2BP2.
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References
- Yin, CC; Jain, N; et al. Identification of a Novel Fusion Gene, IRF2BP2-RARA, in Acute Promyelocytic Leukemia. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK 13:19-22(2015).
- Giraud, G; Stadhouders, R; et al. NLS-tagging: an alternative strategy to tag nuclear proteins. NUCLEIC ACIDS RESEARCH 42:-(2014).
- Blotta, S; Tassone, P; et al. Identification of novel antigens with induced immune response in monoclonal gammopathy of undetermined significance. BLOOD 114:3276-3284(2009).
