INTS5
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Official Full Name
integrator complex subunit 5 -
Overview
INTS5 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large;subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2;(RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)). -
Synonyms
INTS5;integrator complex subunit 5;KIAA1698;INT5;1110055N21Rik;mKIAA1698;RGD1309370;OTTHUMP00000236323
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Myc&DDK
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| INTS5-133H | Recombinant Human INTS5, His-tagged | E.coli | Human | His | 1-322aa | |
| INTS5-8249M | Recombinant Mouse INTS5 Protein | Mammalian Cells | Mouse | His |
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| INTS5-1407H | Recombinant Human INTS5 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| INTS5-2447H | Recombinant Human INTS5 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Ints5-401M | Recombinant Mouse Ints5 Protein, MYC/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| INTS5-4569M | Recombinant Mouse INTS5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| INTS5-4569M-B | Recombinant Mouse INTS5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| INTS5-5086H | Recombinant Human INTS5 Protein, GST-tagged | Wheat Germ | Human | GST |
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| INTS5-5674HF | Recombinant Full Length Human INTS5 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 1019 amino acids |
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Involved Pathway
INTS5 involved in several pathways and played different roles in them. We selected most pathways INTS5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with INTS5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
INTS5 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by INTS5 itself. We selected most functions INTS5 had, and list some proteins which have the same functions with INTS5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | KRT83,TMEM120B,CYFIP1,CC2D1B,MED29,FOXK2,PAXIP1,ARL11,SNX4,PHYHD1 |
Interacting Protein
INTS5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INTS5 here. Most of them are supplied by our site. Hope this information will be useful for your research of INTS5.
CNOT1;Trip11;E2F3;PPP2CA;Cct4;Ppp2r1a;Dennd6a;SKA3;VWA9;Mis12;Tmed10;Chmp4b
Resources
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References
- Oron, E; Mannervik, M; et al. COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster. DEVELOPMENT 129:4399-4409(2002).
