INTS12
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Official Full Name
integrator complex subunit 12 -
Overview
INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large;subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2;(RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)). -
Synonyms
INTS12;integrator complex subunit 12;PHD finger protein 22 , PHF22;hypothetical nuclear factor SBBI22;INT12;SBBI22;PHD finger protein 22;PHF22
Recombinant Proteins
- Rhesus macaque
- Rat
- Zebrafish
- Cynomolgus
- Mouse
- Human
- Mammalian Cells
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
INTS12 involved in several pathways and played different roles in them. We selected most pathways INTS12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with INTS12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
INTS12 has several biochemical functions, for example, protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by INTS12 itself. We selected most functions INTS12 had, and list some proteins which have the same functions with INTS12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SLC9A1,MRPL41,SNX31,MT1G,FKBP2,RAB34,HSPA5,POLG,DIABLO,MTMR7 |
| zinc ion binding | DHX58,KAT7A,PNMA3,ZCCHC3,RNF213,Npepo,APOBEC2B,ESRRGB,CA15C,ADAM9 |
Interacting Protein
INTS12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INTS12 here. Most of them are supplied by our site. Hope this information will be useful for your research of INTS12.
PPP2R1A;PPP2CB;Ppp2ca;PPP2CA;SNW1;Ppp2r1a;Ints4;RNF169;VWA9;NELFA
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