INTS10
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Official Full Name
integrator complex subunit 10 -
Overview
INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large;subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2;(RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)). -
Synonyms
INTS10;integrator complex subunit 10;C8orf35, chromosome 8 open reading frame 35;FLJ10569;INT10;C8orf35
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Chicken
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| INTS10-128H | Recombinant Human INTS10, His-tagged | E.coli | Human | His | 1-347aa | |
| INTS10-3367H | Recombinant Human INTS10 protein, His-tagged | E.coli | Human | His | 37-382 aa | |
| INTS10-11916Z | Recombinant Zebrafish INTS10 | Mammalian Cells | Zebrafish | His |
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| INTS10-2282R | Recombinant Rhesus monkey INTS10 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| INTS10-3357C | Recombinant Chicken INTS10 | Mammalian Cells | Chicken | His |
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| INTS10-8244M | Recombinant Mouse INTS10 Protein | Mammalian Cells | Mouse | His |
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| INTS10-2103R | Recombinant Rhesus Macaque INTS10 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| INTS10-2103R-B | Recombinant Rhesus Macaque INTS10 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| INTS10-4565M | Recombinant Mouse INTS10 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| INTS10-4565M-B | Recombinant Mouse INTS10 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| INTS10-5089H | Recombinant Human INTS10 Protein, GST-tagged | Wheat Germ | Human | GST |
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| INTS10-5662HF | Recombinant Full Length Human INTS10 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 597 amino acids |
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Involved Pathway
INTS10 involved in several pathways and played different roles in them. We selected most pathways INTS10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with INTS10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
INTS10 has several biochemical functions, for example, protein binding,contributes_to protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by INTS10 itself. We selected most functions INTS10 had, and list some proteins which have the same functions with INTS10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to protein binding | TAF10,PAK1,MSH6,CPSF3L,INHA,MLH1,POLR2A,MSH2,ACVR2A,TGFBR3 |
| protein binding | FZD5,NDC80,TMEM66,POLDIP2,MYL6B,WDR18,WDR74,FBXO6,RGP1,KLHL20 |
Interacting Protein
INTS10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INTS10 here. Most of them are supplied by our site. Hope this information will be useful for your research of INTS10.
RAF1;HDGF;PPP2CA;VWA9
Resources
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References
- Obeidat, M; Miller, S; et al. GSTCD and INTS12 Regulation and Expression in the Human Lung. PLOS ONE 8:-(2013).
- Oler, AJ; Cairns, BR; et al. PP4 dephosphorylates Maf1 to couple multiple stress conditions to RNA polymerase III repression. EMBO JOURNAL 31:1440-1452(2012).
