INSC
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Official Full Name
inscuteable homolog -
Overview
In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion;mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling;complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 (PubMed;16458856)). -
Synonyms
INSC;inscuteable homolog (Drosophila);protein inscuteable homolog
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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INSC-5099H | Recombinant Human INSC Protein, GST-tagged | Wheat Germ | Human | GST |
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INSC-5981HF | Recombinant Full Length Human INSC Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 579 amino acids |
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Involved Pathway
INSC involved in several pathways and played different roles in them. We selected most pathways INSC participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with INSC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
INSC has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by INSC itself. We selected most functions INSC had, and list some proteins which have the same functions with INSC. You can find most of the proteins on our site.
Function | Related Protein |
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Interacting Protein
INSC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INSC here. Most of them are supplied by our site. Hope this information will be useful for your research of INSC.
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References
- Du, QS; Stukenberg, PT; et al. A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization. NATURE CELL BIOLOGY 3:1069-1075(2001).